Is the blood count high in encephalitis?

Written by Tang Li Li
Neurology
Updated on September 16, 2024
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Not all cases of encephalitis show an increase in blood counts. Elevated blood counts in encephalitis generally occur in bacterial infections, such as the most common pyogenic meningitis. This can cause a significant increase in blood counts, predominantly with neutrophils. Tuberculous meningitis can also show elevated blood counts, but not as prominently as pyogenic meningitis. In cases of viral infection, such as the common herpes simplex virus infection, patients might experience a decrease in blood counts. This is characterized by a reduction in the total number of white blood cells, a lower proportion of neutrophils, and a possible increase in lymphocyte proportion. If the patient has a concurrent lung infection or other bacterial infections at different sites, there might be an increase in blood counts, which can mask the blood abnormalities originally caused by the viral infection.

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Written by Zhang Hui
Neurology
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How is encephalitis diagnosed?

The diagnosis of encephalitis cannot rely solely on auxiliary examinations; it must depend on the patient's medical history, clinical manifestations, and corresponding physical examination. If a patient presents with fever, headache, nausea, vomiting, and signs of nuchal rigidity upon examination, the possibility of encephalitis should be considered. Additionally, severe cases of encephalitis may exhibit seizures, cognitive changes, and personality alterations. Auxiliary examinations mainly include three types: the first type is imaging studies, primarily brain MRI, which can clearly identify the specific areas of the brain affected and determine which brain lobe is damaged. The second important examination is an electroencephalogram (EEG), which can detect diffuse slow waves, especially a significant presence of delta waves, highly indicative of encephalitis. The third important auxiliary examination is lumbar puncture for cerebrospinal fluid analysis; an increase in white blood cells and protein in the cerebrospinal fluid also suggests inflammation within the skull. Therefore, the main auxiliary examinations for encephalitis include MRI, EEG, and lumbar puncture.

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Written by Zhang Hui
Neurology
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How to prevent encephalitis

Most cases of encephalitis are transmitted through close contact, such as children playing with toys together. It is possible for them to ingest viruses through their hands, which then enter the bloodstream from the stomach and attack the brain. Some cases of encephalitis are also transmitted through the respiratory tract, mainly through droplets. Therefore, in order to prevent encephalitis, it is crucial to maintain hand hygiene, wash hands frequently, and avoid crowded places to prevent respiratory transmission. In addition, to prevent encephalitis, it is important to improve one's physical condition and exercise regularly, as a strong body is less susceptible to viral infections. Finally, it is essential to ensure adequate nutrition for encephalitis prevention, including sufficient daily intake of carbohydrates and dietary fiber, as well as vitamins C and folate, which are crucial for enhancing the body's resistance.

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Written by Li Jiao Yan
Neonatology
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What to do with pediatric encephalitis

If a child develops encephalitis, it is definitely recommended that they be hospitalized for treatment. It is necessary to assess their condition and determine the cause of the encephalitis: is it viral? Bacterial? Or caused by other pathogens? If encephalitis occurs, aggressive treatment is certainly required. In such cases, if the child is discharged from the hospital, they must regularly revisit the hospital for follow-up examinations, and the development of the child's nervous system must be monitored, focusing on motor and cognitive development. Regular assessments at the hospital are definitely required.

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Written by Zhang Hui
Neurology
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Does encephalitis cause fever?

If the patient's encephalitis is caused by a viral infection, they usually exhibit fever, often a high fever with temperatures reaching above 39°C, accompanied by significant symptoms such as headache, nausea, and vomiting. Some patients may also experience cognitive dysfunction, epileptic seizures, and psychiatric symptoms. Therefore, it is crucial to seek medical attention promptly, complete examinations such as electroencephalography, lumbar puncture, and cranial magnetic resonance imaging, and timely apply effective antiviral medications. It should be noted that some encephalitis is caused by autoimmune reactions, referred to as autoimmune encephalitis, which is relatively rare clinically. This type of encephalitis generally does not present with fever. (Please use medications under the guidance of a doctor.)

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Written by Tang Li Li
Neurology
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How is encephalitis caused?

Encephalitis generally falls into two categories: one is infectious inflammation caused by pathogenic infections, and the other is immune inflammation caused by abnormalities in immune mechanisms. Among these, the infectious type is the most common, including viral encephalitis, viral meningitis, tuberculous meningoencephalitis, purulent meningitis, and cryptococcal meningitis, which are associated with infections by viruses, bacteria, Mycobacterium tuberculosis, and Cryptococcus, respectively. Additionally, abnormalities in the immune system often cause autoimmune encephalitis, as well as multiple sclerosis and neuromyelitis optica when involving the brain, and acute disseminated encephalomyelitis, all of which are types of autoimmune encephalitis. The treatment approaches for these two types of encephalitis are different. For pathogen-induced cases, treatment primarily targets the pathogens: antiviral drugs for viral encephalitis, antibiotics for bacterial encephalitis, anti-tubercular therapy involving multiple drugs for Mycobacterium tuberculosis infection, and antifungal drugs, such as amphotericin B, for cryptococcal meningitis. For immune-mediated encephalitis, treatments generally involve immunosuppressants, high-dose corticosteroids, or intravenous immunoglobulins.