Gastric ulcers are primarily caused by several major factors: Helicobacter pylori infection; medications that harm the stomach and damage the gastric mucosa, such as corticosteroids, aspirin, non-steroidal anti-inflammatory drugs, macrolide antibiotics, etc.; long-term irregular eating habits and the consumption of spicy, raw, or irritating foods; long-term mental stress, being in a prolonged state of stress, which can easily lead to gastric ulcers; and excessive stomach acid and pepsin, as well as other physical and biological factors.