How is pyelonephritis diagnosed?

Written by Zhou Qi
Nephrology
Updated on September 18, 2024
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Pyelonephritis is an upper urinary tract infection, with over 95% caused by bacterial infections in areas such as the renal pelvis and calyces, leading to inflammation. As a type of bacterial infection, if a patient's urine routine shows leukocytes and there is percussion pain in the renal area, along with fever, these symptoms combined with the urine examination can essentially lead to a diagnosis. However, a definitive diagnosis requires a culture of clean-catch midstream urine. If the bacteria in two consecutive urine cultures exceed 100,000 per milliliter and are the same type, the patient can be clearly diagnosed with pyelonephritis.

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Written by Zhou Qi
Nephrology
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Principles of treatment for pyelonephritis

Pyelonephritis, also known as an upper urinary tract infection, is a bacterial inflammation, with over 95% being caused by bacterial infections, among which 70% are caused by Escherichia coli. Therefore, as a bacterial infection-induced inflammation, antibiotic treatment is of course necessary. Clinically, third-generation cephalosporins or fluoroquinolone antibiotics are often chosen for bactericidal treatment. For acute pyelonephritis, it is generally recommended that medication be administered for 14 days, alongside measures such as increased water intake and frequent urination. In cases of chronic pyelonephritis, a low-dose, long-course antibacterial treatment, such as using nitrofurantoin, may also be employed, with continuous medication for two months. (Please consult a clinical doctor for specific medication use; do not self-medicate.)

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Written by Zhou Qi
Nephrology
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Is pyelonephritis more serious or nephritis more serious?

Pyelonephritis is an upper urinary tract infection caused by a bacterial infection, leading to an inflammatory response in the urinary system. The severity of this condition can vary. Nephritis, on the other hand, refers to the sterile inflammation within the glomeruli of the kidney, which also varies in severity. Therefore, it is challenging to compare these two diseases in terms of their severity. In the case of pyelonephritis, most conditions are relatively more treatable, and using antibiotics can control acute pyelonephritis. However, a small number of patients may develop severe complications such as perinephric abscess, acute renal failure, renal papillary necrosis, and even death from septic shock. The severity of nephritis also varies, with symptoms ranging from significant proteinuria to mild hematuria. Therefore, a comparison should be based on the specific conditions of the patients. (The use of medications should be under the guidance of a doctor.)

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What foods to eat for pyelonephritis

Pyelonephritis is not nephritis, but a type of bacterial infection. Therefore, as a bacterial infection, there are no specific dietary restrictions for patients. Such patients should ensure adequate intake of fluids, with a recommended daily urine output of over 2000ml. This can help flush the urinary system and wash away some bacteria, reducing bacterial proliferation. Since it involves inflammation, it is advisable to follow a lighter diet, avoiding spicy, stimulating, and greasy foods, and focusing on easily digestible and warm foods.

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Nephrology
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Does pyelonephritis cause a fever?

Pyelonephritis is actually a part of urinary tract infections, which are divided into cystitis and acute pyelonephritis. The main symptoms of cystitis are frequent urination, urgency, and painful urination, among other urinary irritative symptoms, and these do not involve fever. However, if cystitis is not treated in time, it can worsen into acute pyelonephritis, which then presents with symptoms such as fever and back pain. The fever with acute pyelonephritis can be quite high, often exceeding 38 or 39 degrees Celsius, and might last for two to three days. At this point, treatment requires anti-infective medications, which should be continued for two weeks without any interruption. If the treatment duration is insufficient, pyelonephritis may recur. It is important to drink plenty of water, urinate frequently, and avoid holding in urine. Drinking lots of water can help flush out bacteria from the urine early on, promoting a quicker recovery from the illness.

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Written by Zhou Qi
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How to check for pyelonephritis?

Pyelonephritis, also known as upper urinary tract infection, is mostly caused by bacterial infection and the inflammatory response of the urinary system. The screening for this disease involves routine urine tests. Presence of white blood cells in the urine, coupled with symptoms like fever and back pain, can lead to a preliminary diagnosis. However, to confirm the diagnosis and identify the specific infecting pathogen, a culture of midstream urine is needed. Generally, to exclude certain causes of pyelonephritis, it is also necessary for the patient to have blood sugar levels checked and an ultrasound of the urinary system conducted. These tests can confirm whether the patient has diabetes, urinary system stones, or obstructions in the urinary system. Male patients can also undergo a prostate ultrasound to rule out urinary obstruction caused by prostate enlargement. These examinations can also help determine why the patient might have developed pyelonephritis.