Does pyelonephritis cause a fever?

Written by Pan Wu Shan
Nephrology
Updated on September 24, 2024
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Pyelonephritis is actually a part of urinary tract infections, which are divided into cystitis and acute pyelonephritis. The main symptoms of cystitis are frequent urination, urgency, and painful urination, among other urinary irritative symptoms, and these do not involve fever. However, if cystitis is not treated in time, it can worsen into acute pyelonephritis, which then presents with symptoms such as fever and back pain. The fever with acute pyelonephritis can be quite high, often exceeding 38 or 39 degrees Celsius, and might last for two to three days. At this point, treatment requires anti-infective medications, which should be continued for two weeks without any interruption. If the treatment duration is insufficient, pyelonephritis may recur. It is important to drink plenty of water, urinate frequently, and avoid holding in urine. Drinking lots of water can help flush out bacteria from the urine early on, promoting a quicker recovery from the illness.

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Written by Li Liu Sheng
Nephrology
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How is pyelonephritis treated?

Whether it is the treatment of acute pyelonephritis or chronic pyelonephritis, first of all, personal hygiene should be emphasized, physical fitness should be enhanced, water intake should be increased, and urination should be frequent. In addition, for patients with acute pyelonephritis, the main treatment is the use of sensitive antibiotics, which can be either semi-synthetic penicillin or cephalosporins, and fluoroquinolone antibiotics can also be used. For chronic pyelonephritis, if the patient has urinary anatomical or functional abnormalities, such as the presence of urinary stones or urinary obstruction, active surgical treatment can be considered to relieve the obstruction. Furthermore, patients with chronic pyelonephritis who also have hypertension and edema can appropriately use antihypertensive drugs and diuretics to control blood pressure and edema, which can play a role in protecting kidney function. (The use of medications should be conducted under the guidance of a doctor.)

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Written by Zhou Qi
Nephrology
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How to diagnose pyelonephritis?

For the diagnosis of pyelonephritis, it is first necessary to confirm the diagnosis. Generally, patients should first undergo routine urine tests. In these tests, the presence of white blood cells and positive nitrites, along with clinical symptoms such as back pain, blood in urine, and fever are common. A routine blood test often shows elevated white blood cells and C-reactive protein. These indicators together suggest the presence of pyelonephritis. Furthermore, a culture of a clean-catch midstream urine sample can be done. If the bacteria grow to a certain quantity, it can also help in confirming the diagnosis of pyelonephritis. Additionally, to assess complications associated with pyelonephritis, it is necessary to perform blood tests for kidney function and an ultrasound of the urinary system to rule out conditions such as acute renal failure, renal papillary necrosis, and perinephric abscess, among others.

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Written by Zhou Qi
Nephrology
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Pyelonephritis is an infection of the kidneys

In fact, pyelonephritis is not really nephritis; it is actually a type of bacterial inflammatory infection. Bacteria can infect many parts of the body. If the urinary system is infected and it reaches the renal pelvis and calyces, it is referred to as pyelonephritis. Over 95% of pyelonephritis cases are caused by bacterial infections, and 70% are due to Escherichia coli. Generally, this bacteria enters the urinary system from the urethral opening and ascends to the renal pelvis and calyces, where it proliferates and causes an inflammatory response. The main clinical symptoms of the patient are fever and back pain, and the patient may also experience gross hematuria (visible blood in urine).

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Written by Pan Wu Shan
Nephrology
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Can pyelonephritis lead to pregnancy?

Pyelonephritis is actually a urinary tract infection. It is not the same as nephritis, so do not confuse the two. Thus, pregnancy is completely feasible for someone with pyelonephritis; as long as the infection is treated, the urine test shows negative results, and there are no white blood cells, pregnancy can occur without any impact. Currently, the treatment for pyelonephritis is anti-infection therapy. Since the bacteria have entered the kidney via the urethra, this treatment needs to last for two weeks. If the treatment duration is insufficient, there could be a recurrence of pyelonephritis. Additionally, it is important to drink plenty of water, urinate frequently, avoid holding urine, consume more than 2500 milliliters of water daily, and maintain a light diet avoiding spicy and irritating foods.

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Written by Zhou Qi
Nephrology
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How is acute pyelonephritis treated?

Acute pyelonephritis is a problem caused by an infection, also known as an upper urinary tract infection. Therefore, the treatment plan for this disease should be based on the pathogen. The vast majority of acute pyelonephritis is caused by bacterial inflammation, so antibiotics are often required. It is generally recommended that patients should receive intravenous antibiotic treatment to kill the bacteria, choosing the antibiotics sensitive to the results of urine culture. After 10 to 14 days of treatment, the condition of acute pyelonephritis can usually be controlled in most cases. The patient's body temperature will gradually decrease, symptoms of back pain will ease, and the white blood cells in the urine will also disappear. Only a very few cases of acute pyelonephritis are difficult to treat because such patients may have predisposing factors to urinary tract infection such as diabetes and urinary system stones. (Specific medication use should be conducted under the guidance of a doctor.)