IgA nephropathy is a very common glomerular disease in clinical settings and is one of the main causes of uremia. IgA nephropathy is most commonly seen in adolescents, particularly in males. The cause of IgA nephropathy is currently unclear, but the clinical manifestations of patients with IgA nephropathy are numerous and vary in severity. For patients with milder IgA nephropathy, it is important to maintain a healthy lifestyle, avoid staying up late, overworking, and infections. Frequently staying up late can aggravate the condition, leading to significant proteinuria and even worsening kidney function. Therefore, it is crucial for patients with IgA nephropathy to regularly monitor their urinalysis, kidney function, and blood pressure, maintain a regular lifestyle, and avoid various adverse lifestyle impacts. Of course, once the condition worsens, it is important to seek medical attention promptly and pursue active treatment.