Obvious symptoms of pulmonary hypertension

Written by Li Hai Wen
Cardiology
Updated on August 31, 2024
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Pulmonary hypertension is a relatively common disease in everyday life. Based on the causes of pulmonary hypertension, it can be divided into two categories: primary and secondary pulmonary hypertension. Regardless of the type of pulmonary hypertension, patients often exhibit certain symptoms, such as chest tightness and shortness of breath, which are the most common symptoms. In severe cases, some patients may even experience syncope. When pulmonary hypertension affects the heart, causing right ventricular enlargement, patients often show signs of right heart failure, such as shortness of breath, difficulty breathing, lower limb edema, and gastrointestinal symptoms, such as nausea and abdominal distension.

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The harms of pulmonary arterial hypertension during pregnancy

Pulmonary hypertension is categorized into mild, moderate, and severe stages. If it is mild pulmonary hypertension, pregnancy generally does not have a major impact. However, for those with moderate or especially severe pulmonary hypertension, pregnancy can be very dangerous for both the mother and the fetus. As the fetus grows, pulmonary hypertension can lead to ischemia and hypoxia, which can worsen over time. The mother is likely to develop symptoms of acute heart failure, severely endangering her life. Additionally, it can cause intrauterine hypoxia for the fetus, leading to miscarriage or stillbirth. Therefore, pregnancy is not recommended for patients with moderate, and particularly severe, pulmonary hypertension.

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Early symptoms of pulmonary arterial hypertension

It depends on what disease causes pulmonary hypertension. There are several common causes of pulmonary hypertension, one of which is a pathological change in the pulmonary artery itself. Early on, there may be signs of mild increases in pulmonary artery pressure, possibly accompanied by slight right heart dysfunction. At this stage, symptoms such as mild hypotension and hypoxia might occur, manifesting as dizziness and fatigue. If the pulmonary hypertension is due to a disease of the lungs themselves, such as changes in the lung interstitium, then early symptoms of hypoxia will be more apparent, with chest tightness, slight breathing difficulties, and feelings of suffocation. If pulmonary hypertension is caused by conditions such as pulmonary embolism—specifically, an embolism in a smaller branch—the increase in pulmonary artery pressure may not be significant and will also be mild. This may be accompanied by a slight drop in blood pressure and mild breathing difficulties; however, because it is mild pulmonary hypertension, these symptoms are not severe and might include slight respiratory difficulty, mild chest tightness, shortness of breath, and mild dizziness. Therefore, early symptoms of pulmonary hypertension are typically not pronounced and generally do not attract special attention from patients.

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What to do with mild pulmonary hypertension?

Pulmonary artery hypertension is a relatively common disease in daily life. Based on the different pulmonary artery pressures, it can be divided into mild, moderate, and severe pulmonary artery hypertension. When the right heart catheter measures pulmonary artery pressure between 30 to 50 mmHg, this situation often belongs to mild pulmonary artery hypertension. So, what should one do if diagnosed with mild pulmonary artery hypertension? Generally, mild pulmonary artery hypertension is not serious and usually does not cause noticeable symptoms, so no special treatment is needed. However, having mild pulmonary artery hypertension does not mean it can be taken lightly. It is important to undergo regular examinations under the guidance of a doctor, identify the cause of the increased pulmonary artery pressure, and treat the symptoms timely.

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Does pulmonary hypertension require oxygen therapy?

Whether pulmonary arterial hypertension requires oxygen therapy primarily depends on the patient's blood oxygen saturation level at rest. Generally, it is recommended to measure the oxygen saturation for patients with pulmonary arterial hypertension. Due to intrapulmonary shunting and shunting between the left and right heart during pulmonary arterial hypertension, arterial and venous blood mix directly, resulting in very low blood oxygen saturation in patients. Generally speaking, if the measured blood oxygen saturation at rest is below 90%, such patients often need oxygen therapy. Even if it does not drop below 90%, patients with moderate to severe pulmonary arterial hypertension also require oxygen therapy. Oxygen therapy can improve hypoxia, significantly dilating the pulmonary vessels and thus alleviating symptoms of high pulmonary artery pressure. It is very valuable for improving patient prognosis and survival time.

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How is pulmonary hypertension treated?

The treatment of pulmonary hypertension mainly focuses on identifying the cause. For idiopathic pulmonary hypertension, treatment primarily targets vascular constriction, endothelial damage, thrombus formation, and heart failure. This is to restore the tension, resistance, and pressure of the pulmonary vessels, improve the patient's sexual function, increase cardiac output, and improve quality of life. The main treatments include: 1. Drug therapy, which includes calcium channel blockers, prostacyclin, nitric oxide, endothelin receptor antagonists, and related anticoagulants. Anticoagulants do not improve symptoms, but can slow down disease progression and improve prognosis in some aspects. However, in cases of right heart failure, hepatic congestion, and ascites, cardiotonic diuretics are used, such as digoxin and anti-calcium channel blockers, which can cause adverse reactions like decreased myocardial contractility. But these drugs should be administered under the guidance of a doctor. In advanced stages of pulmonary arterial hypertension, heart-lung transplantation may be considered.