The clinical symptoms of pulmonary hypertension primarily include: 1. Shortness of breath, which is the most common symptom of pulmonary hypertension. Many patients experience shortness of breath as their initial symptom, which is often related to physical activity. As the condition progresses, the shortness of breath tends to worsen. 2. Some patients may also experience chest pain, dizziness, or fainting. 3. Some patients may cough up blood, usually only a small amount, but occasionally there can be a significant amount. 4. Patients with pulmonary hypertension caused by chronic obstructive pulmonary disease may experience repeated symptoms of coughing and coughing up phlegm. 5. Patients with pulmonary hypertension often experience fatigue and weakness.