Tetanus

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Written by Liu Huan Huan
General Surgery
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Is tetanus an anaerobic bacterium?

Tetanus is a specific infection often associated with trauma. In addition to various traumas, it can also occur in parturient women and newborns under unsanitary conditions. The pathogen is Clostridium tetani, an obligate anaerobe that stains positive under Gram staining conditions. Normally present in the intestines of humans and animals, it is distributed in nature and common in soil. This type of bacteria has strong resistance to environmental conditions and can withstand boiling.

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Written by Zhang Peng
General Surgery
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Can I breastfeed after getting a tetanus shot?

Current research indicates that lactating women are not contraindicated for tetanus vaccination; the main contraindication is allergy to the tetanus vaccine. Generally, if there are high-risk factors for tetanus infection, timely wound debridement and care should be performed, followed by early administration of passive immunization with tetanus vaccine. Generally, tetanus antitoxin can be used based on the results of a skin test. If the skin test result is strongly positive, its use should be avoided, and tetanus immunoglobulin should be chosen instead. The effective metabolic period of tetanus immunoglobulin is about three weeks. If high-risk factors for infection still exist beyond this time limit, timely enhancement of immune therapy should be considered. Regarding the tetanus vaccine, it is generally advised that the earlier it is administered, the better, as early administration can neutralize the tetanus toxin already present in the blood. However, if the tetanus toxin has already bound to nerve cells, treatment becomes relatively difficult.

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Written by Liu Huan Huan
General Surgery
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How is tetanus diagnosed?

The diagnosis of tetanus requires comprehensive consideration. If the patient has a history of trauma with skin or mucosal wounds, and shows signs of muscle spasms, such as difficulty opening the mouth, stiffening of the neck, and increased reflexes, the possibility of a tetanus infection should be considered. Further, a culture of the wound can be conducted to see if Clostridium tetani can be cultured. If the culture is positive, a definitive diagnosis can be made. Additionally, tetanus needs to be differentiated from other diseases such as purulent meningitis, rabies, epilepsy, hysteria, and so on.

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Written by Liu Huan Huan
General Surgery
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Which department do I go to for a tetanus shot?

Tetanus shots are widely used clinically, and patients generally receive the injection after sustaining an injury. Therefore, it is recommended that patients visit the surgical department. If at a community hospital, they should go to the surgical outpatient clinic. If in a secondary or tertiary hospital, patients can go to the surgical outpatient clinic or the emergency surgery department for treatment. After wound treatment, they can receive a tetanus shot as required. Thus, patients usually go to the surgical department or emergency surgery for the tetanus injection.

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Written by Gao Jun
Emergency Surgery
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Can tetanus be cured?

Tetanus has a high mortality rate from infection, but it is not incurable. Even in primitive tribes in Africa, as long as the patient can survive the initial complications such as respiratory muscle spasms leading to suffocation, heart failure, lung infections, etc., they may be lucky to survive. However, in our daily lives today, if we accidentally sustain skin injuries or abrasions, we must not take them lightly and should head to the hospital to follow the doctor's advice. If a tetanus antitoxin injection is needed, it must be administered. Do not neglect it due to inconvenience, as it may lead to severe consequences. The initial symptoms of tetanus might include general weakness, muscle soreness, and spasms of the chewing muscles, which can later lead to severe muscle contractions and forceful spasms throughout the body. The patient remains fully conscious and can painfully experience the disease. Most patients may die from complications such as respiratory muscle spasms, suffocation, heart failure, and lung infections.

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Written by Xu Jun Hui
General Surgery
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Can I take a bath after getting a tetanus shot?

It's not recommended to take a bath immediately after receiving a tetanus shot. First, the wound requiring a tetanus shot may either be deep, heavily contaminated, or relatively large. After receiving a tetanus shot in the buttocks or the deltoid muscle of the upper arm, it is essential to enhance wound dressing changes and keep the wound dry, which is why bathing is not advised. If it's just a simple tetanus injection site, it can generally be exposed to water a few hours later. However, other wounds on the body should be kept dry. Therefore, it is better to take a bath when wounds on other parts of the body have healed well to avoid worsening infections and delaying healing.

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Written by Ma Xian Shi
General Surgery
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How to administer a tetanus shot: steps

First, an allergy test must be conducted. Based on the results of the allergy test, the application of tetanus antitoxin is decided. The allergy test involves drawing 0.1 ml of antitoxin serum, diluting it with 0.9 ml of isotonic saline, and then injecting 0.05 to 0.1 ml of the diluted solution intradermally on the flexor side of the forearm. An equivalent amount of isotonic saline is injected on the other forearm as a control. Observe for 15-30 minutes. If there is no nodule or resistance at the injection site, it is a negative result. Patients with a negative result can have the rest of the original liquid injected subcutaneously. If a red nodule of about one centimeter or resistance appears at the serum injection site, the allergy test is positive. In this case, a desensitization injection is needed. The desensitization injection involves diluting the required injection fluid and the antitoxin serum with isotonic saline to ten times the volume and administering it subcutaneously in divided doses. After dilution to ten times the volume, which is 10 ml, the initial dose of 1 ml is administered, followed by 2 ml, 3 ml, and 4 ml, with each injection spaced 30 minutes apart until completed.

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Written by Gao Sen
General Surgery
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Tetanus 0.1ml how many units

In general, the dose of tetanus toxoid is 1500 international units per dose, approximately 1 ml per dose, and generally about 150 international units per 0.1 ml, which can be referred to the instructions. The use of tetanus toxoid should be avoided blindly and should be administered under the guidance of a physician. Additionally, wound cleaning and disinfection should be performed before administering tetanus toxoid. Furthermore, anti-infection treatment should be considered based on the contamination of the wound.

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Written by He Zong Quan
General Surgery
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How to avoid tetanus with minor wounds

If minor wounds are not properly handled, they can lead to serious problems, including tetanus. Treatment for minor wounds should be based on the integrity of the skin, the depth of the wound, and whether the object causing the wound was rusty. For simple minor wounds where the integrity of the skin is maintained and only abrasions are present, disinfection of the affected skin area may suffice. If the wound has compromised the integrity of the skin and is deep, especially if caused by rusty, sharp objects, it is necessary to thoroughly remove any foreign materials, clean the wound, and suture it. Dressing changes might be required, along with tetanus vaccination to prevent tetanus infection.

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Written by Sun Ming
General Surgery
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Why is tetanus given three times?

Tetanus is often derived from horse serum, which is a heterologous protein that many people might be allergic to. This is why a sensitivity test is done before administering tetanus shots; a positive allergy test indicates the presence of this antigen in your body, which can lead to an allergic reaction. To prevent such allergic reactions, desensitization is performed through intramuscular injections, which means administering the tetanus vaccine in three separate doses. This approach helps avoid allergies or even severe anaphylactic shock that might occur from the tetanus shot.