Pericardial effusion


The causes of reduced urine output due to pericardial effusion
Pericardial effusion can potentially lead to reduced urine output. This occurs because in patients with pericardial effusion, the diastolic function of the heart is restricted, limiting the blood volume during the diastolic phase. This, in turn, reduces the amount of blood pumped by the heart during the systolic phase, ultimately leading to ischemia. To ensure the blood supply to vital organs like the brain, the heart reduces its blood supply, impacting the glomerular filtration rate, and thus symptoms of reduced urine output can occur. Additionally, symptoms such as limb edema, shortness of breath, respiratory difficulties, and chest tightness often accompany these. As pericardial effusion can cause congestion in the gastrointestinal tract, some patients may also experience abdominal distension, nausea, and vomiting among other digestive symptoms. A pericardial effusion ultrasound can definitively diagnose a pericardial effusion.


Does pericardial effusion cause proteinuria?
Pericardial effusion generally does not cause proteinuria. Conditions that cause proteinuria mainly include hypertension and diabetes, which are common causes of proteinuria in the elderly. Additionally, patients with glomerulonephritis may also experience proteinuria, but this is more often seen in younger people. Pericardial effusion primarily affects the heart, leading to reduced cardiac pumping and resulting in ischemia and hypoxia, which can cause symptoms such as dyspnea, fatigue, and limb edema. In cases of significant pericardial effusion, cardiac tamponade may occur, leading to a sharp drop in blood pressure, with the patient experiencing profuse sweating, cold and clammy skin, and confusion, which are signs of hypotensive shock and often require emergency pericardial fluid drainage to alleviate symptoms.


How is pericardial effusion treated?
The treatment of pericardial effusion mainly includes the following measures: First, treatment should be based on the different causes of pericardial effusion. For example, pericardial effusion caused by infection should be treated with anti-infection measures, and pericardial effusion caused by heart failure should be treated with anti-heart failure measures; Second, for a large amount of pericardial effusion or pericardial effusion causing cardiac tamponade, active pericardiocentesis and drainage should be provided to relieve the pressure on the heart caused by the pericardial effusion; Third, when severe pericardial effusion causes hypotension or even shock, volume expansion and pressor agents should also be administered; Fourth, for some patients with pericardial effusion, if the absorption of the effusion is not effective after general treatment, corticosteroids may be appropriately administered.


Can pericardial effusion be drained?
In cases of moderate or large pericardial effusion, fluid can be drained, such as when the thickness of the pericardial effusion exceeds two centimeters. Draining the fluid can relieve the symptoms caused by the pericardial effusion, improve cardiac blood supply, and also allow for the collection of samples for routine and biochemical analysis of the effusion, as well as pathological examination. By analyzing the drained fluid, it is possible to determine the nature of the effusion, such as whether it is an exudate or a transudate. This can then further help in determining the cause of the effusion, where exudates are often caused by factors such as tuberculosis and cancer, while transudates are often due to heart failure or hypoproteinemia and other factors.


Does pericardial effusion increase or decrease pulse pressure?
In general, if a patient develops pericardial effusion, the pulse pressure difference typically decreases, especially the gap between diastolic and systolic pressures. This is because pericardial effusion can weaken the contractility of the heart chambers, leading to either decreased diastolic pressure or increased systolic pressure, thus reducing the pulse pressure difference. If pericardial effusion is timely addressed and corrected, this condition can improve. Currently, it is recommended that patients actively monitor changes in blood pressure. If there is a history of hypertension, it is necessary to actively use antihypertensive medications to treat and control this condition.


Will pericardial effusion cause an increase in troponin levels?
In general, if a patient is diagnosed with pericardial effusion, troponin levels might also increase under stress conditions. This is because troponin is primarily used as a marker to assess myocardial infarction. An increase in troponin levels suggests the possibility of a myocardial infarction. However, under stress conditions, especially with pericardial effusion, troponin levels can rise. During this period, it is also advisable to perform an electrocardiogram or a cardiac echocardiography on the patient for a more definitive diagnosis. A mere increase in troponin levels does not conclusively indicate a problem; it is necessary to consider the patient’s current symptoms and results from other diagnostic tests.


Can tuberculous pleurisy cause pericardial effusion?
Tuberculous pleurisy can also cause pericardial effusion. Firstly, tuberculous pleurisy is actually caused by the tubercle bacillus, a type of immune response in the human body that manifests as inflammation in the serous cavity. The serous cavities include various types such as the pleura surrounding the lungs, the pericardium around the heart, and the peritoneum in the abdomen. Therefore, tuberculous inflammation can occur in multiple serous cavities, including the pleura, pericardium, and abdominal cavity. Of course, when diagnosing, one cannot solely rely on the presence of effusion in multiple serous cavities to diagnose tuberculous pleurisy. Instead, it is essential to aspirate the pleural fluid and test certain markers in it, such as adenosine deaminase and lactate dehydrogenase. Most importantly, the presence of acid-fast bacilli in the fluid should be checked. If detected, it can generally be diagnosed as tuberculous.


Should fluid intake be controlled for pericardial effusion?
Whether pericardial effusion requires control of water intake depends on the cause of the pericardial effusion, as there are many reasons for it, such as heart failure, tuberculous pericarditis, tumors, and hypoproteinemia. Pericardial effusion caused by heart failure requires water intake restriction, as excessive drinking can aggravate the symptoms of heart failure. However, for pericardial effusion caused by tuberculosis or tumors, water intake does not significantly affect the pericardial effusion, so there is no need to deliberately control water consumption. Patients with pericardial effusion should quit smoking and avoid alcohol in their daily lives, as smoking and drinking can exacerbate the symptoms of pericardial effusion. Additionally, patients should not overexert themselves.


Is pericardial effusion prone to recurrence?
Whether pericardial effusion is prone to recurrence depends on the causes of the effusion. There are many causes of pericardial effusion, such as organic heart disease, heart failure, tumors, tuberculosis, and hypoproteinemia, all of which can lead to the development of pericardial effusion. Among these, pericardial effusion caused by tuberculous pericarditis will not recur as long as standardized anti-tuberculosis treatment is administered and the tuberculosis is controlled. However, pericardial effusion caused by heart failure may recur repeatedly because heart failure itself can also recur. Moreover, pericardial effusion caused by tumors, if the tumors cannot be eradicated, often also recurs.


How to eliminate pericardial effusion and ascites?
The methods for eliminating pericardial effusion and ascites mainly include the following aspects: First, etiological treatment, which involves treating the underlying causes of pericardial effusion and ascites. For instance, if tuberculosis is the cause, standard anti-tuberculosis treatment should be administered. Once tuberculosis is under control, the ascites and pericardial effusion will naturally resolve. Second, symptomatic treatment, such as the use of diuretic drugs, can reduce the phenomenon of pericardial effusion and ascites in some patients. If there is hypoproteinemia, appropriate supplementation with albumin can effectively improve the effusion. Third, fluid drainage treatment, if the amount of pericardial effusion and ascites is large, puncture and fluid drainage can be performed to alleviate the pericardial effusion and ascites, and at the same time, further investigate the cause of the effusion.