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Li Fang Fang
Hematology
About me
After graduation, I have been working in the Hematology Department at Kaifeng Central Hospital, engaging in clinical work. I have gained certain clinical experience in common diseases in the field of hematology, and have also assisted other clinical departments in auxiliary treatments.
Proficient in diseases
Specializes in common diseases of hematology, such as leukemia, hemophilia, anemia, lymphoma, thrombocytopenia, tetanus, hypoglycemia, aplastic anemia, neonatal hemorrhage, vitamin deficiencies, and other autoimmune diseases.
Voices
Can anemia cause headaches?
Anemia can cause headaches because when anemia occurs, the entire body is in a state of ischemia and hypoxia. The severity of anemia varies, and so does the extent of ischemia and hypoxia in the body. When anemia is severe, the body is in a significantly compromised state of ischemia and hypoxia. Ischemia and hypoxia in the nervous system can manifest as headaches. Additionally, symptoms can include a feeling of heavy-headedness, and even cerebral infarction, which are caused by anemia. After correcting the anemia by transfusing red blood cells, the headaches will alleviate.
Is aplastic anemia contagious?
Aplastic anemia is a bone marrow failure disease and is not infectious; it cannot be transmitted. Aplastic anemia is considered a hematological disorder and should be routinely diagnosed and treated in the department of hematology. It falls under the category of bone marrow failure diseases, and its main clinical manifestations are infection, anemia, and bleeding, with a complete blood count showing a decrease in all blood cells. Patients with aplastic anemia can be divided into acute aplastic anemia and chronic aplastic anemia, and there are some differences in the treatment of the two.
How is acute leukemia treated?
The treatment for acute leukemia is chemotherapy. Chemotherapy can be administered orally or intravenously, and the choice between oral or intravenous chemotherapy depends on the type of acute leukemia. For patients with acute leukemia, if chemotherapy alone can effectively control the disease or achieve a cure, then there is no need for allogeneic hematopoietic stem cell transplantation. However, if chemotherapy alone cannot control the disease, and the patient is considered at high risk and of suitable age, then allogeneic hematopoietic stem cell transplantation should be considered.
How to test for leukemia?
Patients with leukemia should first undergo a routine blood test. Some leukemia patients' routine blood tests may indicate leukemia, such as when white blood cell counts are abnormally high, exceeding 50*10^9/L, and can even reach more than 100*10^9/L, which highly suggests leukemia. At this point, bone marrow biopsy, bone marrow immunotyping, and chromosome tests are needed to further clarify the type of leukemia. In addition, risk stratification in leukemia patients is also necessary through genetic mutations and chromosome analysis.
Can anemia cause tinnitus?
Anemia can lead to tinnitus. The occurrence of tinnitus due to anemia often indicates that the anemia is severe. At this time, transfusion of red blood cells as supportive treatment, and correcting the anemia afterwards, will make the tinnitus disappear. The reason anemia causes tinnitus is that it leads to a state of ischemia and hypoxia in various organs of the body. In the auditory system, this is manifested as tinnitus; in the nervous system, it is also manifested as dizziness, headache, a feeling of heaviness in the head, and even cerebral infarction; in the cardiovascular system, it is manifested as palpitations and panic.
Is chronic myeloid leukemia scary?
Chronic myeloid leukemia, though a type of leukemia, is not terrifying because there are targeted drugs available for it, namely tyrosine kinase inhibitors. These inhibitors have been developed into first, second, and third-generation products. Most cases of chronic granulocytic leukemia can achieve clinical remission after oral administration of tyrosine kinase inhibitors. Some patients might experience a blast crisis, acceleration phase, or relapse during treatment, but they can switch to higher-grade tyrosine kinase inhibitors or undergo allogeneic hematopoietic stem cell transplantation. Thus, chronic myeloid leukemia is no longer considered a frightening disease. (Please use medication under the guidance of a doctor.)
What tests are done for leukemia?
Patients with leukemia need to be further classified to determine if it is acute leukemia or chronic leukemia, whether it is acute myeloid leukemia or acute lymphoblastic leukemia in the case of acute leukemia, and whether it is chronic myeloid leukemia or chronic lymphocytic leukemia in the case of chronic leukemia. Therefore, in addition to routine blood tests, leukemia patients also need to undergo bone marrow cytology, immunophenotyping, testing for 43 types of leukemia fusion genes, chromosome tests, etc., to further clarify the subtype of leukemia. After the subtype is clarified, a treatment plan is selected based on the specific type.
Can leukemia be cured?
Leukemia is a broad category of diseases. Some leukemia patients can achieve clinical cure through oral chemotherapy or intravenous chemotherapy, while others can only achieve cure through allogeneic hematopoietic stem cell transplantation. Among them, chronic granulocytic leukemia can be clinically cured through oral chemotherapy due to the availability of targeted drug treatments, resulting in a longer survival period. In the case of acute promyelocytic leukemia, the advent of drugs like retinoic acid and arsenic trioxide has enabled patients to achieve clinical cure through a combination of oral and intravenous chemotherapy. However, many other types of leukemia often require allogeneic hematopoietic stem cell transplantation to reach clinical cure.
What indicators are used to diagnose iron deficiency anemia?
For iron deficiency anemia, a complete blood count should first be considered. The blood count presenting as microcytic hypochromic anemia often suggests the possibility of iron deficiency anemia. Microcytic hypochromic anemia is characterized by a decrease in hemoglobin, a decrease in mean corpuscular volume, a decrease in mean corpuscular hemoglobin concentration, and a decrease in mean corpuscular hemoglobin. When the complete blood count indicates the possibility of iron deficiency anemia, further investigation into iron-related indices is required, such as decreased serum iron, decreased ferritin, decreased transferrin saturation, and increased soluble transferrin receptor capacity.
Can iron deficiency anemia be cured?
Iron deficiency anemia is treatable, but it is essential to identify the cause of the iron deficiency. The treatment of iron deficiency anemia is divided into two main parts. The first part involves iron supplementation, which can be administered orally or intravenously, with intravenous supplementation generally being more effective and faster. The second part is crucial: identifying the cause of the iron deficiency. For example, common causes in women of childbearing age include heavy menstrual periods, while older patients often suffer from gastrointestinal tumors or ulcers, and in children, the common cause is usually nutritional deficiency. It is vital to treat the underlying cause.