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Cui Fang Bo
Oncology
About me
Specializing in the clinical and scientific research of anticancer drugs, especially targeted therapies. Serving as the principal investigator, leading a project funded by the National Natural Science Foundation of China. As the first author, published multiple academic papers, including 6 English-language papers indexed in SCI, with the highest impact factor being 6.49.
Proficient in diseases
Treatment with anticancer drugs, especially the use of targeted therapy for tumors.
Voices
What should I do if nasopharyngeal carcinoma causes vomiting?
Patients with nasopharyngeal carcinoma who exhibit vomiting should first determine the cause of the vomiting. For instance, if vomiting is due to the gastrointestinal reactions caused by radiotherapy and chemotherapy, medications such as serotonin receptor antagonists, corticosteroids, and NK-1 receptor blockers should be used to alleviate the side effects of the treatment. Additionally, nasopharyngeal carcinoma patients might experience projectile vomiting due to brain metastasis, which results in increased intracranial pressure. It is essential first to confirm the presence of brain metastasis through CT and MRI scans of the head. If brain metastasis is confirmed, localized treatment such as radiotherapy should be administered. Medications like mannitol and glycerol fructose should be used concurrently to reduce intracranial pressure and relieve the projectile vomiting. (Please use medications under the guidance of a doctor.)
What fruits are good to eat for thyroid cancer?
Many fruits can be consumed by patients with thyroid cancer. Thyroid cancer currently has a high incidence rate in our country. For patients suspected of having thyroid cancer, a thyroid nodule puncture can be performed. After the puncture, if diagnosed with thyroid cancer, surgery is the preferred treatment. Patients who have undergone surgery often suffer from malnutrition due to the surgical expenditure, and therefore, special attention should be paid to the arrangement of nutritional intake. In terms of nutritional intake, consuming fresh fruits and vegetables is a very good choice. There are no specific contraindications indicating that patients with thyroid cancer cannot eat certain foods. Also, when it comes to consuming fruits, many types of fruits are available for selection. It is important to note that one should avoid eating raw, cold, or spoiled fruits; other fresh fruits and vegetables can be consumed.
Will early-stage liver cancer cause a low-grade fever?
Patients with early-stage liver cancer may experience low-grade fevers, primarily due to the following two reasons: First, tumor fever. In the early stages of liver cancer, some tumor cells can release tumor mediators into the bloodstream, affecting the function of the temperature regulation center and causing the patient to develop a fever. This type of tumor fever is usually not very high, remaining below 38.5°C, without concurrent symptoms or signs of infection. A complete blood count typically indicates that the total number of white blood cells and the proportion of neutrophils are not elevated. The second scenario involves patients in the early stages of liver cancer experiencing fever due to concurrent infections. These patients often present with symptoms and signs related to infection, such as coughing up phlegm, abdominal pain and diarrhea, and urinary frequency, urgency, or pain. The proportion of white blood cells and neutrophils is significantly increased in these cases.
Early symptoms of breast cancer
The symptoms of early-stage breast cancer mainly include breast lumps, abnormal nipple discharge, and changes in breast skin. Breast cancer is a common type of malignant tumor among women in China, with adenocarcinoma being the most common pathological type, although other types can also be seen clinically. Patients exhibiting abnormal breast lumps, abnormal nipple discharge, and changes in breast skin should consider the possibility of breast cancer. Patients suspected of having breast cancer should undergo breast imaging tests, including mammography and breast MRI, among others. Patients in whom abnormal breast masses are found during imaging tests can obtain a definitive diagnosis by surgical removal or percutaneous biopsy. Patients diagnosed with breast cancer should undergo surgical treatment as soon as possible.
How to reduce fever in late-stage liver cancer
For late-stage liver cancer patients experiencing fever, antipyretic treatment should be based on different circumstances. If the fever is due to an infection, it often exceeds 39℃ and is accompanied by symptoms and signs related to the infection, such as cough and yellow sputum, abdominal pain, diarrhea, frequent urination, urgency, and painful urination. In such cases, antibiotics should be used for anti-infective treatment, along with antipyretic analgesics for fever reduction. If the fever is due to tumor fever or interventions like liver procedures, there are no infection-related factors, usually the temperature does not exceed 38.5℃, and there are no symptoms or signs related to infection. The treatment primarily involves the use of antipyretic analgesics for fever reduction.
What are the differences between colon cancer and rectal cancer?
The fundamental difference between colon cancer and rectal cancer lies in their locations of occurrence. Both are collectively referred to as colorectal cancer, which is one of the more prevalent malignancies of the digestive system in China. Colon cancer originates from the mucosa of the colon, while rectal cancer originates from the mucosa of the rectum, with different points of origin. In terms of treatment, there are significant differences between colon and rectal cancer. In surgical treatment, both cancers typically require surgery as the first choice. However, patients with colon cancer can preserve their anus, whereas some patients with low rectal cancer might face situations where anus preservation is not possible. In internal medicine, the chemotherapy drugs used for colon and rectal cancer are quite similar. In terms of radiation therapy, there are notable differences; radiation treatment is generally not included for colon cancer but is an important treatment method for rectal cancer.
Can the anus be preserved if the rectal cancer is 3 cm away from the anus?
When rectal cancer is 3cm from the anus, it generally isn't possible to preserve the anus. Currently, the commonly used surgical methods for rectal cancer are the Dixon and Miles techniques. Generally, the threshold is 5cm from the anus; when the tumor is within 5cm of the anus, it often necessitates a Miles procedure, which does not preserve the anus. When the tumor is more than 5cm from the anus, an anus-preserving Dixon procedure can be performed. However, in considering the radical resection of rectal cancer, preserving the anus should not be the primary choice; instead, the main goal should be curative.
Can melanoma without metastasis avoid chemotherapy?
For patients with melanoma that has not metastasized, direct surgical removal can be performed, and chemotherapy is not necessary after surgery. Melanoma is a malignant tumor that originates from melanocytes and can occur in many parts of the body, with melanomas of the skin and mucous membranes being the most common, accounting for about 70% of all cases. Once melanoma is diagnosed, if there is no distant metastasis to other organs, curative surgical removal can be performed. Postoperative treatment mainly involves immunotherapy, not systemic chemotherapy. For patients who are diagnosed with distant organ metastasis, systemic chemotherapy and immunotherapy are required.
What are the early symptoms of rectal cancer?
Early symptoms of rectal cancer include a foreign body sensation in the anus, bloody stools, changes in stool shape, and more. Rectal cancer is a prevalent malignant tumor of the digestive tract in China, originating from the rectal mucosa. The most common pathological type is adenocarcinoma, with other pathological types being relatively rare. Patients exhibiting bloody stools or changes in stool shape should consider the possibility of rectal cancer. Patients suspected of having rectal cancer should undergo a rectal examination and colonoscopy as soon as possible. Abnormal masses in the rectum can be detected during the rectal examination and colonoscopy. Tissue can be taken from the mass for pathological diagnosis. Patients diagnosed with rectal cancer via pathology are primarily treated with surgery, and those who cannot undergo surgery should receive combined radiotherapy and chemotherapy treatment.
What should I do if I have liver cancer and a fever of 38 degrees Celsius?
Liver cancer patients experiencing a fever of 38°C can be seen in the following scenarios: The first type is tumor-related fever. In liver cancer patients, especially those in the advanced stages or with large tumors, a fever of around 38°C can occur in the absence of infection symptoms. This tumor fever is related to various mediators released into the blood by the tumor. The second type is infectious fever. Cancer patients undergoing anti-tumor treatment may experience immunosuppression and concurrent infections. This type of fever often exceeds 38.5°C but can also occur around 38°C in the early stages, often accompanied by symptoms of infection such as coughing, sputum production, abdominal pain, and diarrhea. The third type is treatment-related fever. Patients with liver cancer may experience a fever of around 38°C on the day of and several days following interventional treatments.