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Yan Chun
Oncology
About me
Graduated from the Clinical Medicine Department of Qingdao Medical College, has been working in the Oncology Department since 2001, obtained the qualification of attending physician in the same year. Promoted to attending physician in 2003. Qualified as associate chief physician in 2011. Participated in advanced studies at Jinan Cancer Hospital from June to November 2015. Serves as a youth member of the Chemical Therapy Committee in Shandong Province, youth member of the Elderly Therapy Committee of the Qingdao Anti-cancer Association, and a member of the Biologic Therapy Committee of the Qingdao Anti-cancer Association.
Proficient in diseases
Chemotherapy, radiotherapy, deep hyperthermia, targeted therapy, and endocrine therapy for various tumors such as stomach cancer, colorectal cancer, lung cancer, breast cancer, ovarian cancer, and pancreatic cancer.
Voices
Will the cervix rot in the late stages of cervical cancer?
In late-stage cervical cancer, some patients experience severe local tumor infiltration which can lead to tissue necrosis. This necrosis often leads to secondary infections, thereby causing severe complications such as septic shock. In treating such patients, in addition to administering anti-tumor therapies, the primary treatment involves the use of antibiotics to control the infection, to prevent potentially fatal complications such as septic shock. Furthermore, the disease in most patients with late-stage cervical cancer typically presents as widespread dissemination. This dissemination is primarily manifested by metastasis to distant lymph nodes and infiltration of surrounding tissues, as well as metastasis to remote organs like the lungs, liver, and other abdominal organs. Clinically, patients mainly exhibit symptoms related to these metastatic sites.
Does nasopharyngeal carcinoma cause excessive phlegm?
Patients with nasopharyngeal carcinoma often exhibit clinical manifestations of excessive sputum, which is considered to be symptomatic of middle to late stages of nasopharyngeal carcinoma. For patients with middle to late stages of nasopharyngeal carcinoma, their immunity is compromised, and this decrease in immunity becomes more pronounced after receiving anti-tumor treatments such as radiotherapy and chemotherapy. As a result, patients are highly susceptible to concurrent infections, primarily manifesting symptoms related to the respiratory system such as coughing, sputum production, fever, and chest pain. Additionally, late-stage nasopharyngeal carcinoma patients may also experience metastasis to the lungs. When lung metastasis occurs, patients may develop obstructive pneumonia, which can also lead to the clinical presentation of excessive sputum. Moreover, some patients may exhibit increased sputum production as a side effect of anti-tumor treatments.
What are the causes of cervical cancer?
Clinically, the causes of cervical cancer include the following aspects: First, the incidence of cervical cancer significantly increases in women who start sexual activity at an early age or have multiple sexual partners. Second, genetic factors also play a certain role in the development of cervical cancer. Third, the female population with malnutrition or chronic inflammatory diseases of the cervix can also lead to a high incidence of cervical cancer. Fourth, women with sexually transmitted diseases, such as gonorrhea and genital warts, can also cause cervical cancer. Fifth, some women with viral infections may also undergo carcinogenic changes in the cervix, thus forming cervical cancer.
Is stage T2 throat cancer considered early stage?
Stage T2 of laryngeal cancer is considered early-stage laryngeal cancer, as the current clinical staging of laryngeal cancer primarily follows the international TNM staging system. According to the TNM staging criteria, "T" represents the extent of the primary tumor in laryngeal cancer, "N" represents the condition of the regional lymph nodes, and "M" indicates distant organ metastasis. The staging of laryngeal cancer is mainly categorized based on different TNM statuses, with "T" divided into five categories based on the extent of the tumor invasion: T0, T1, T2, T3, and T4. If the patient is only at stage T2 without any N and M metastasis, it is clinically considered early-stage.
Formation of teratoma
Teratoma is a type of tumor disease originating from germ cells, clinically classified into benign and malignant categories. The specific cause of teratoma formation is currently unclear; it is considered to be due to abnormal mutations occurring during the development of germ cell tumors, thereby forming tumors. The formation of teratomas also involves some inducing factors, such as familial genetic history. Due to specific genetic mutations in the family, the incidence of familial teratomas increases. Additionally, some external infections are also related to the occurrence of teratomas, ultimately leading to their formation.
What are the early symptoms of ovarian cancer?
The early symptoms of ovarian cancer are not severe or common clinically. Some patients may experience abdominal distension and pain. Some may have menstrual irregularities, such as prolonged or shortened menstrual cycles, increased menstrual flow, or irregular bleeding outside of menstruation. Additionally, a small number of patients may experience pelvic pain due to local tumor compression caused by ovarian cancer. This pain occasionally radiates to the perineal area and is generally mild, rarely affecting the patient's quality of life. Furthermore, a minor proportion of ovarian cancer patients, particularly those with tumors having endocrine functions, may exhibit symptoms associated with paraneoplastic syndromes.
What changes occur in the hair during the early stages of liver cancer?
Liver cancer is a common type of tumor in the digestive system in China, and patients with early-stage liver cancer generally do not experience significant changes in their hair. This is because the tumors in early-stage liver cancer patients are relatively small, and the treatment often involves surgical removal, which does not require chemotherapy or other anti-tumor treatments, so the impact on the patient's hair is minimal. As the disease progresses, some patients may need to undergo chemotherapy or other anti-tumor treatments, which can lead to hair loss or changes in hair color. However, hair changes after chemotherapy in liver cancer patients are generally reversible, and hair can regrow after the end of chemotherapy. Changes in hair color, on the other hand, are generally caused by pigment deposition induced by some chemotherapy drugs.
Is colon cancer invading the submucosa early stage?
The lesion of colon cancer has invaded the submucosa, which could be either early stage or advanced stage, as the staging of colon cancer is determined by three factors. First is the primary lesion of the colon cancer itself, second is the regional lymph node metastasis, and third is distant metastasis. The invasion of the submucosa in colon cancer is just indicative of the status of the primary lesion; we also need to consider the regional lymph nodes and distant metastasis to determine the stage. If the lesion has invaded the submucosa without regional lymph node metastasis and no distant metastasis, then its clinical stage is early. If the lesion of colon cancer has not only invaded the submucosa but also has regional lymph node metastasis or has metastasized to distant organs, then the condition would be considered as advanced stage.
Is it better for melanoma to have a BRAF mutation or not to have a BRAF mutation?
Melanoma is a type of skin cancer with a very high malignancy. Before targeted drugs were available, patients with BRAF gene mutations indicated a poorer prognosis for melanoma. The mutation of the BRAF gene promotes the progression of melanoma. However, with the advancement of current clinical research, patients with melanoma having BRAF mutations have a better therapeutic effect with BRAF inhibitor targeted therapy. After adopting this targeted drug treatment, the cure rate has significantly increased, and the prognosis of patients has markedly improved. Therefore, patients with BRAF-mutated melanoma can benefit from targeted therapy.
What are the precursors of pancreatic cancer?
Pancreatic cancer is a malignant tumor that occurs in the digestive system clinically. Due to the hidden location of the pancreas, early symptoms of pancreatic cancer are generally not obvious. When individuals with a family history of pancreatic cancer exhibit unexplained fatigue or abdominal discomfort, or rapidly progressive jaundice symptoms in a short period, and if patients also have diseases such as diabetes, the possibility of pancreatic cancer should be considered. An abdominal CT scan, MRI, and other radiological examinations should be completed quickly. For identified pancreatic space-occupying lesions, early biopsy through puncture or direct exploratory laparotomy should be performed as soon as possible for treatment.