

Yan Xin Liang

About me
Graduated from Nanhua University, engaged in pediatric work for over 10 years, and have further studied at Hunan Children's Hospital, Xiangya Hospital, and Beijing Children's Hospital.
Proficient in diseases
Diagnosis and treatment of common diseases in pediatric internal medicine, especially skilled in the diagnosis and treatment of pediatric respiratory system and neurological diseases, such as pediatric convulsions, epilepsy, asthma, and lung infections...

Voices

Does phenylketonuria affect intelligence?
Phenylketonuria is a common amino acid metabolic disease, primarily caused by a deficiency of phenylalanine hydroxylase in the metabolic pathway of phenylalanine, preventing phenylalanine from converting into tyrosine. This leads to the accumulation of phenylalanine and its ketones in the body, which are then excreted in large amounts through urine. Its clinical manifestations are not uniform. The main clinical characteristic is intellectual disability, thus it does affect intelligence. Additionally, it can present various neuropsychiatric symptoms such as increased muscle tone, hyperreflexia, agitation, hyperactivity, convulsions, etc. It can also lead to reduced skin pigmentation and yellowing of hair among other symptoms. This disease can impact intelligence.

Do children with colds need to take cephalosporins?
Pediatric colds can be divided into viral colds and bacterial infections that cause upper respiratory tract symptoms. Generally speaking, 90% of cases are commonly viral colds. Viral colds are mainly treated symptomatically. Appropriate antiviral medications can be used, and antipyretics can be given during fevers. Also, drinking plenty of warm water and using some Chinese patent medicines for clearing heat and detoxifying can be sufficient. However, if the viral infection lasts a long time, it can easily lead to a secondary bacterial infection. In such cases, antibiotics can be used. Initially, oral penicillin antibiotics should be chosen, and cephalosporin antibiotics can also be selected for anti-infection treatment. If considering bacterial infection causing upper respiratory tract infection, such as acute tonsillitis caused by streptococcus infection, oral penicillin or cephalosporin antibiotics for anti-infection treatment can be used. Therefore, it is essential to choose medications based on the specific situation. (Medication should be used under the guidance of a doctor.)

How is phenylketonuria tested?
Phenylketonuria is a treatable inherited metabolic disease, and early diagnosis is essential for early treatment. Currently, we have generally implemented a newborn disease screening system that requires collecting peripheral blood by pricking the heel of newborns after three days of breastfeeding, dropping the blood onto specialized filter paper and sending it to a screening laboratory for phenylalanine concentration measurement. If the concentration exceeds the confirmed value, further differential diagnosis and confirmation are needed. If treatment can begin early, especially within two to three weeks after birth, the prognosis is generally good. Normally, the concentration is less than 120 µmol/L; a fetal concentration of 1200 µmol/L would be considered mild phenylketonuria.

Can a baby take a bath when they have a cold?
When babies have a cold, it is generally not recommended to give them a bath soak, but showering is acceptable. This is because soaking for an extended period may worsen the symptoms of the cold. However, if the baby has a fever, showering with warm water can help reduce their temperature, which is an effective physical cooling measure. But if soaking in a bath, the extended time in the water and the slight dilation of pores may allow cold to penetrate further into the body, potentially worsening the cold symptoms. Therefore, under these circumstances, it is temporarily advised against giving babies a bath soak. However, a medicinal herbal bath is a different matter.

What are the common causes of diarrhea in children?
Some common causes of childhood diarrhea include infectious and non-infectious diarrhea. Causes of infectious diarrhea include bacteria, viruses, amoebic dysentery, etc. Common viruses such as rotavirus, norovirus, etc. Common bacterial infections include Escherichia coli, Shigella, and other bacteria. Additionally, intestinal amoebic pathogens can also cause diarrhea. Some causes of non-infectious diarrhea include lactose intolerance and food allergies, among others.

Is tetralogy of Fallot a chromosomal problem?
Tetralogy of Fallot is the most common cyanotic congenital heart disease in childhood, consisting of four defects: ventricular septal defect, obstruction of the right ventricular outflow tract, overriding aorta, and right ventricular hypertrophy. It is a type of congenital heart disease, which generally stems from abnormal cardiovascular development during fetal life, resulting in cardiovascular malformations not controlled by chromosomes. The malformation of the cardiovascular system is mainly caused by genetic factors, environmental factors, and their interactions. The exact cause of this congenital heart disease has not been fully identified yet, indicating that it is not a chromosomal disease but a result of cardiovascular developmental abnormalities during fetal life.

Phenylketonuria positive means what?
Phenylketonuria is an autosomal recessive inherited disease and is the most common congenital amino acid metabolism disorder. Generally, if the activity of phenylalanine hydroxylase in the body is reduced, or if there is a deficiency in its coenzyme tetrahydrobiopterin, the concentration of phenylalanine in the blood and tissues will increase, and phenylpyruvic acid, phenylacetic acid, and phenyllactic acid in the urine will also increase. Generally, newborns may not show any special clinical features at first. Often, the first test results may be high due to maternal influence or dietary factors, which can cause these elevated indicators in newborns. If the second test is normal, there usually isn’t a significant problem. A third test can also be performed; if the third test still shows no issues, then phenylketonuria can be ruled out. Generally, if phenylketonuria is diagnosed, it should be treated promptly and properly.

Can eczema in children appear all over the body?
Infant eczema, also known as atopic dermatitis, is a chronic recurrent inflammatory skin condition that generally occurs during infancy. The main causes are likely related to genetic factors, environment, immunity, biological factors, and more. The rash typically features chronic recurrent dermatitis in areas such as the face, neck, antecubital fossa, and popliteal fossa. Occasionally, the eczema may also involve the chest, abdomen, back, and limbs, although this is less common.

Treatment methods for childhood diarrhea
Firstly, it is important to pay attention to the baby’s response and the condition of their urination. If the baby shows poor spirit response and less urination, it often indicates dehydration, which can be mild, moderate, or severe. Generally, mild to moderate dehydration can be treated with oral rehydration solutions, which include electrolytes replenishment. However, in cases of severe dehydration, which may suggest hypovolemic shock, emergency intravenous fluids are necessary to expand blood volume, and it is crucial to go to the hospital promptly. Additionally, oral probiotics like bifidobacteria can be administered to regulate the intestinal flora. Montmorillonite powder can also be given to protect the gastrointestinal mucosa and stop diarrhea. If bacterial infection is suspected to be the cause of diarrhea, appropriate antibiotics should be used to treat the infection, which can be administered orally or intravenously depending on the severity of the infection. Meanwhile, the baby's urination, spirit response, skin elasticity, and symptoms of dry mouth should be closely monitored to comprehensively evaluate the treatment effectiveness.

How many days will it take for the baby to recover from a cold?
Generally speaking, if a baby has a cold caused by a common viral infection and receives symptomatic treatment, the symptoms can usually be controlled within three to five days. If it is a severe cold or influenza, the symptoms can be more severe and may include repeated fever, runny nose, and sneezing, lasting longer, about seven days, or even up to ten days. If there is a bacterial infection following the cold, the duration may be even longer and would require specific analysis based on the actual situation.