The treatment of flat warts mainly includes several aspects: physical therapy, topical medication therapy, and systemic medication therapy. Physical therapy for local application includes methods such as laser, cryotherapy, and microwave. This is mainly suitable when there are few skin rashes, as fewer lesions do not cause much trauma. If there are many lesions, it is recommended to use topical medication therapy and oral or injectable medication therapy. Topical medication therapy includes antiviral medications like acyclovir and penciclovir, topical immunomodulatory drugs like interferon, which also have antiviral effects, as well as topical fluorouracil and topical retinoids. Additionally, there is oral medication therapy, which includes oral antiviral drugs such as acyclovir, as well as oral retinoids. There are also medications available to boost immunity and modulate the immune system, such as thymosin and interferon. However, all these treatments should be carried out under the guidance of a doctor.