Is depression prone to recurrence?

Written by Pang Ji Cheng

Psychiatry and Psychology

Updated on May 03, 2025

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Depression is a disease with a high incidence rate, so in clinical practice, the treatment of depression requires systematic standardization, adequate dosages, and full courses of treatment, and it is also a disease with a high cure rate. After standardized systemic treatment, a cure rate of over 85% can be achieved. However, nearly 50% of the patients may relapse one year after undergoing standardized treatment. Therefore, during the treatment process, not only pharmacotherapy is needed but also psychotherapy and self-adjustment methods. A comprehensive and systematic treatment can ultimately improve the cure rate of patients, reduce the recurrence rate, and effectively treat the disease.

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What is the depressive mood of depression like?

Patients with depression primarily exhibit symptoms of low mood. They often experience persistent sadness and pessimism. Patients might find it difficult to feel happy, appear gloomy, and are unable to experience joy, particularly in activities that they used to find interesting. In severe cases, they might feel hopeless, in despair, and have thoughts of death, leading to an overwhelming sense that each day is unbearably long. Furthermore, patients might feel that life isn't worth living and that their existence has no meaning, which can lead to thoughts or actions of suicide or self-harm. In this emotional state, their self-evaluation is also typically low; they might feel utterly worthless, viewing themselves as a burden on their family and a parasite in society. Thus, feelings of worthlessness, helplessness, despair, and self-blame are significantly more pronounced.

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Is mild depression normal?

Patients with mild depression, although also experiencing symptoms such as low mood, decreased interest, reduced motivation, slow thinking, and reduced volition, may have difficulty falling asleep and frequently wake up during sleep, among other related symptoms. However, patients often retain most of their social functions, causing some disturbance to daily life and work. Through self-adjustment, standardized psychotherapy, and medication, patients often achieve good treatment outcomes. Sometimes, the symptoms of some patients are relatively mild, and they may appear normal outwardly, but their inner experience is indeed pathological. Therefore, it is still necessary to undertake standardized, systematic, and scientific treatment to achieve clinical recovery.

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Can someone with mild depression go to work?

Patients with mild depression can go to work. Those with mild depression may exhibit lighter symptoms such as mood decline, fatigue, and decreased interest. Often, patients may have difficulty sleeping; however, their social functions or most other functions are generally unaffected, with only minor impacts on their work and social activities. If patients are functionally capable of handling their jobs, depressive symptoms can be improved through behavioral training. Therefore, in clinical practice, patients with mild depression are encouraged to continue working, which further activates their energy and motivation, enhancing their positivity and initiative, and improving treatment outcomes. Additionally, psychotherapy and pharmacotherapy can also achieve good therapeutic effects for patients with mild depression. Systematic and standard treatments should be continued to ultimately reach clinical recovery.

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Written by Pang Ji Cheng

Psychiatry and Psychology

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Can mild depression recur?

Patients with mild depression also have the possibility of relapse. Clinical research investigations have found that systematic antidepressant treatment can lead to clinical recovery in 85% of patients. However, even with persistent and standardized treatment, nearly one-fifth of patients still experience relapse. This signifies that some patients may have a relapse rate exceeding 70% if they cease treatment. For those who recover, there is still a one-fifth chance of relapse within six months, and nearly half might relapse within two years after the initial episode. Therefore, relapse is a significant challenge for depression patients. Thus, treatment should be systematic and standard, including pharmacotherapy. Additionally, psychotherapy plays a crucial role in treating depression by improving patients' irrational cognitive patterns and adjusting their cognitive reconstruction systems, ultimately achieving a healed state.