Is moderate depression serious?

Written by Pang Ji Cheng
Psychiatry and Psychology
Updated on April 18, 2025
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Patients with moderate depression are quite serious. The core manifestations in clinical practice include low mood, inability to feel happy, reduced energy, and predominantly negative thinking. These symptoms often lead to a decline in the patient's social and occupational functioning, affecting their work, study, life, social interactions, and family life. Patients typically present with a lack of desire to groom themselves or pay attention to their attire, and they often have a dull gaze and an unpleasant emotional experience. There is generally a lack of energy and interest. In terms of cognitive thinking, they often exhibit feelings of worthlessness, pessimism, guilt, uselessness, or despair. Behaviorally, they often show psychomotor retardation, meaning they walk and act slowly, think sluggishly, cannot relax, and sometimes exhibit symptoms of restlessness.

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Psychiatry and Psychology
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Can mild depression cause fantasies?

In clinical settings regarding patients with mild depression, hallucinatory symptoms generally do not occur. It is commonly believed in clinical practice that patients with moderate to severe depression might experience hallucinations. However, according to the new mental illness diagnostic standard, IC11, it is considered that patients with mild depression may also exhibit symptoms of delusions and hallucinations. Therefore, the presence of hallucinations and delusions in patients should be assessed based on the severity of the condition. Typically, the occurrences of hallucinations and delusions indicate a higher severity of depression, generally moderate to severe. If diagnosed with psychotic depression, the clinical approach should involve the combined treatment using antidepressants and antipsychotic medications to address both the psychotic and depressive symptoms effectively.

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Written by Zhou Yan
Geriatrics
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Is elderly depression easy to treat?

Depression in the elderly is difficult to treat because compared to younger patients, depression in the elderly tends to last longer with an average duration often exceeding one year, and episodes occur more frequently, often becoming chronic. Additionally, the prognosis for elderly depression is worse compared to other age groups, primarily due to the coexistence of cerebrovascular diseases and other physical comorbidities, recent acute illnesses, long-term ongoing diseases, as well as the presence of delusions and a lack of social support systems. Thus, depression in the elderly is quite challenging to treat.

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Written by Pang Ji Cheng
Psychiatry and Psychology
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What medication is used for depression?

The medications commonly used for depression in clinical settings are selective serotonin reuptake inhibitors, primarily used to increase serotonin levels in the patient's brain to improve depressive symptoms. Representative drugs in clinical use include paroxetine, sertraline, fluoxetine, fluvoxamine, citalopram, and escitalopram. There are also medications that inhibit the reuptake of both serotonin and norepinephrine, such as venlafaxine and duloxetine. Additionally, there's a type of antidepressant that acts on norepinephrine and is specifically serotonergic, with mirtazapine being the main drug. These medications are considered modern antidepressants and have a relatively significant clinical efficacy. Of course, there are also traditional tricyclic and tetracyclic antidepressants, which are not recommended as first-line treatments in clinical settings due to their more adverse reactions. (Please follow a doctor's guidance regarding the use of specific medications.)

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Written by Pang Ji Cheng
Psychiatry and Psychology
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How is depression diagnosed?

The diagnosis of depression in clinical settings involves four aspects: First, the collection of medical history, which includes understanding the onset, progression, treatment, and outcome of the illness, as well as past treatment experiences, etc. Second, psychiatric assessment, involving examinations with the patient concerning their sensations, perceptions, consciousness, thinking, emotions, intelligence, memory, self-control, willpower, and other aspects. Third, the use of scales to measure depression, which includes self-rating scales or observer-rating scales for depression to assess the severity of the patient's condition. Fourth, through related auxiliary examinations, excluding physical illnesses that may cause symptoms of depression. Ultimately, the diagnosis of depression is determined by integrating information from these four areas.

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Does postpartum depression require medication?

When suffering from postpartum depression, it can be treated with medication. This treatment method can help control negative emotions in new mothers. It can also alleviate some physical discomfort, reducing the damage caused by depression during treatment. However, breastfeeding should be suspended if medication is being taken. In addition to medication, psychological treatment is also necessary. Adjusting one's mental state is very important, as most cases of postpartum depression are caused by an unhealthy psychological foundation. (The use of medication should be conducted under the guidance of a professional doctor.)