For the comprehensive treatment of malignant (breast cancer), it needs to be specifically addressed based on case analysis, considering the patient's physical condition, economic factors, and other circumstances. There isn't a one-size-fits-all treatment plan suitable for everyone, as each case requires specific analysis. The treatment options for breast cancer include, firstly, surgery, which can be either a mastectomy or breast-conserving surgery, depending on lymph node metastasis and pathological staging. The second option includes radiation therapy, the third is endocrine therapy, the fourth is chemotherapy, the fifth is targeted therapy, and the sixth and subsequent options may include immunotherapy.