Chronic conjunctivitis is a chronic inflammation of the conjunctiva caused by various reasons, with complex etiology, mainly manifested as mild conjunctival congestion and a small amount of mucous secretion, often affecting both eyes. Chronic conjunctivitis is not self-limiting and can be difficult to treat. Treatment is targeted based on different causative factors, along with the appropriate use of antibiotic eye drops and ointments. In cases of chronic staphylococcal conjunctivitis, erythromycin responds quite well, while a broad-spectrum antibiotic eye drop, aminoglycoside eye drops, or ointments may be chosen for other bacterial causes. For cases where the above medications are ineffective, a conjunctival scraping can be performed for bacterial culture and sensitivity testing, and the medication can be adjusted based on the results.