Pulpitis can only improve by undergoing dental treatment, with most cases clinically arising from the progression of dental caries. If dental caries are not promptly filled in the early stages to halt their progression, bacteria can further infect and cause nerve damage. After a nerve-killing treatment for pulpitis, pain generally subsides. The specific duration depends on the nerve-killing medication used; some act quickly, usually within 2 days or 48 hours, killing the dental nerve and thus alleviating the pain of pulpitis. Others may act slowly, requiring about 2 weeks, or approximately 14 days.