neuroblastoma cure rate

Written by Chen Yu Fei
Neurosurgery
Updated on November 17, 2024
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Neuroblastoma is relatively likely to be a malignant tumor, typically characterized by rapid growth of malignant tumors.

In the early stages of the disease, it often adheres to surrounding tissues, making it difficult to completely remove through surgery. Even with surgical treatment, the outcomes are generally modest, and recurrence is likely to occur shortly after surgery. Once recurrence occurs, the malignancy of the tumor will continue to increase.

For these patients, the prognosis is poor. It is generally recommended to undergo surgical treatment early, followed by radiotherapy and chemotherapy to potentially extend the patient's lifespan, but it is usually difficult to cure.

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Written by Chen Yu Fei
Neurosurgery
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Early symptoms of neuroblastoma

For patients with neuroblastoma, the early stages of the disease often manifest as mild headaches, dizziness, nausea, and vomiting. The symptoms are relatively mild and can be significantly alleviated by taking oral pain relief medications. Therefore, the condition often does not receive adequate attention, leading to missed diagnoses. As the tumor size increases, the original symptoms such as headaches and dizziness will significantly worsen. Some patients may even experience optic nerve atrophy, papilledema, reduced visual fields, and vision deficits. When such conditions occur, patients often undergo cranial CT or MRI scans to confirm the presence of neuroblastoma.

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Written by Kang Li
Neurosurgery
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Symptoms of Neuroblastoma

Typical symptoms of neuroblastoma include anemia and fatigue, excitement, no weight gain or weight loss, or irregular fever. The initial symptoms in the course of a short disease are not typical. Early diagnosis is difficult. Nonspecific symptoms include fatigue, loss of appetite, fever, joint pain. Those occurring within the skull display a bit of central nervous system cursing symptoms and symptoms of intracranial hypertension. Main manifestation. Occurrence outside the skull depends on the location of the tumor and the metastatic sites. Involvement of the thoracic cavity can cause chest and back pain and difficulty breathing, involvement of the abdominal cavity is characterized by abdominal distension, constipation, dysentery, and involvement of the spinal canal manifests as reduced strength in the trunk and limbs, and motor and sensory disturbances.

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Written by Chen Yu Fei
Neurosurgery
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Early symptoms of neuroblastoma

For patients with neuroblastoma, in the early stages, due to the small size of the tumor, there generally lacks clear clinical signs or symptoms. Most patients experience mild headaches, dizziness, nausea, and vomiting, accompanied by a certain degree of vertigo. However, in most cases, these symptoms can be tolerated. Patients often have episodic attacks, with a persistent worsening condition. Later, as the tumor grows further, it may lead to an exacerbation of existing symptoms such as headaches, dizziness, nausea, and vomiting. Some patients may also experience abnormalities in the sensation of one side of the body, manifested as numbness, pain, and a tingling sensation.

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Written by Chen Yu Fei
Neurosurgery
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Neuroblastoma treatment

Neuroblastoma is relatively considered a malignant tumor, and its growth rate is quite rapid. It often adheres to surrounding tissues in the early stages, which makes it very difficult to completely remove surgically. However, even so, it is still advisable to opt for surgical treatment once neuroblastoma is detected. The tumor should be completely removed surgically, and a small amount of tumor tissue should be retained for pathological examination after removal. Based on the results of the pathological examination, it will be determined whether additional treatments such as radiotherapy or chemotherapy are needed. Furthermore, since some neuroblastomas are sensitive to radiotherapy, it is recommended to promptly take the patient to a local hospital for treatment after surgery.

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Written by Chen Yu Fei
Neurosurgery
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How is neuroblastoma diagnosed?

For patients with neuroblastoma, diagnosis is primarily through the symptoms, signs, detailed physical examinations, medical history inquiries, and most importantly, radiological data, which includes CT scans or MRI of the head. Definitive diagnosis requires surgical removal of the tumor. A small amount of tumor tissue is retained after excision and used for pathological examination to confirm the diagnosis. Neuroblastoma is categorized as an epithelial-like malignant tumor, indicative of a high degree of malignancy. In most cases, early in the disease, the tumor adheres to surrounding tissues, which greatly complicates complete surgical removal, and most patients have a poor prognosis.