Early symptoms of neuroblastoma

Written by Chen Yu Fei
Neurosurgery
Updated on January 09, 2025
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For neuroblastoma, in the early stages of the disease, mild headaches, dizziness, nausea, and vomiting often occur, but the symptoms are relatively mild and most can be tolerated. As the disease gradually progresses and the tumor volume begins to increase, it compresses the surrounding brain tissue and cranial nerves, causing the patient to exhibit certain degrees of headache, dizziness, nausea, vomiting, and other clinical manifestations. As the tumor volume further increases and cerebral edema becomes apparent with elevated intracranial pressure, it may lead to cranial nerve dysfunction in patients. For instance, it might trigger epileptic seizures or cause patients to experience hemiplegia, aphasia, and other clinical manifestations. Once these symptoms occur, it is advisable to visit a local hospital early for treatment.

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Written by Chen Yu Fei
Neurosurgery
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What should be avoided in the diet for neuroblastoma?

Patients with neuroblastoma should be cautious with their diet and avoid foods that are overly greasy or spicy. It's also advisable to limit or avoid carbohydrate-rich or fried foods and those high in cholesterol. If the patient has allergies, they should avoid seafood products, which contain abundant animal proteins and can trigger allergic reactions, potentially leading to allergic dermatitis or allergic asthma. Additionally, some fruits, such as durian or mango, may also induce allergic reactions, so it is best to consume them sparingly or not at all.

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Written by Kang Li
Neurosurgery
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Symptoms of Neuroblastoma

Typical symptoms of neuroblastoma include anemia and fatigue, excitement, no weight gain or weight loss, or irregular fever. The initial symptoms in the course of a short disease are not typical. Early diagnosis is difficult. Nonspecific symptoms include fatigue, loss of appetite, fever, joint pain. Those occurring within the skull display a bit of central nervous system cursing symptoms and symptoms of intracranial hypertension. Main manifestation. Occurrence outside the skull depends on the location of the tumor and the metastatic sites. Involvement of the thoracic cavity can cause chest and back pain and difficulty breathing, involvement of the abdominal cavity is characterized by abdominal distension, constipation, dysentery, and involvement of the spinal canal manifests as reduced strength in the trunk and limbs, and motor and sensory disturbances.

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Written by Chen Yu Fei
Neurosurgery
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How does neuroblastoma heal itself?

Neuroblastoma cannot completely heal by itself. Once neuroblastoma is detected, patients should be promptly taken to local hospitals for treatment, be hospitalized, and undergo skull CT or MRI scans. If necessary, enhanced MRI scans can be conducted to clarify the current location of the tumor and its relationship with surrounding tissues, and to determine the surgical plan. The tumor should be completely removed through surgery. After the surgery, a small amount of tumor tissue should be kept for pathological slides to assess the need for radiotherapy, chemotherapy, or other related treatments based on the results of the pathological examination. For some elderly and frail patients who cannot tolerate surgery, Gamma Knife treatment can also be considered.

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Written by Chen Yu Fei
Neurosurgery
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How to check for neuroblastoma?

For the examination of neuroblastoma, we generally recommend a neurological examination to help determine whether there are any clear positive signs, as well as to inquire about medical history and family history to judge if there are any cases of neuroblastoma among family members. Additionally, detailed laboratory tests, routine blood tests, routine urine tests, and biochemical tests, including tumor-related diagnostics, can help in making assessments. Of course, the most accurate and crucial examinations are CT or MRI scans of the head. If necessary, an enhanced MRI scan of the head can be conducted to further evaluate the location, nature, severity of the tumor, and its relationship with the surrounding neural and vascular tissues, which helps provide a basis for further surgical treatment.

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Written by Chen Yu Fei
Neurosurgery
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Early symptoms of neuroblastoma

For patients with neuroblastoma, in the early stages, due to the small size of the tumor, there generally lacks clear clinical signs or symptoms. Most patients experience mild headaches, dizziness, nausea, and vomiting, accompanied by a certain degree of vertigo. However, in most cases, these symptoms can be tolerated. Patients often have episodic attacks, with a persistent worsening condition. Later, as the tumor grows further, it may lead to an exacerbation of existing symptoms such as headaches, dizziness, nausea, and vomiting. Some patients may also experience abnormalities in the sensation of one side of the body, manifested as numbness, pain, and a tingling sensation.