Acute upper respiratory infections are very common in clinical settings. These patients typically have compromised immune systems, and the infections—caused by viruses, bacteria, or other pathogens—lead to various symptoms such as fever, nasal congestion, runny nose, sneezing, and coughing. Depending on the specifics of viral or bacterial infections, active and effective antiviral or antibacterial treatments can be administered. Additionally, moxibustion can be used as an auxiliary treatment to help these patients. The sites for moxibustion usually include major acupuncture points such as Dazhui (GV14) or Hegu (LI4), among others. The appropriate moxibustion treatment can be determined based on each patient’s specific situation, potentially assisting in the alleviation of symptoms associated with acute upper respiratory infections.