When pheochromocytoma becomes malignant, it can be cured through clinical approaches, although malignant pheochromocytoma mainly refers to those that have distant metastases. It primarily exhibits aggressive growth or is accompanied by metastases to other organs, and surgery cannot completely remove it, leading to a high recurrence rate post-surgery. Generally, the five-year survival rate for patients with malignant pheochromocytoma does not exceed half.

If treated with chemotherapy or arterial embolization, it can control the patient's blood pressure and alleviate the tumor burden, thereby extending the survival period.

In summary, the treatment of malignant pheochromocytoma is relatively challenging, has a high recurrence rate, and poses a significant threat to human life.