Hypoglycemia is caused by what?

Written by Li Lang Bo
Endocrinology
Updated on April 21, 2025
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Hypoglycemia is most commonly seen in patients with type 2 diabetes. During the treatment of diabetes, hypoglycemia can occur due to excessive use of medication or insulin, failure to eat on time after exercise, or decreased appetite without appropriately reducing the medication. Another common cause is insulinoma, a type of tumor that secretes excessive insulin, resulting in lowered blood glucose levels. A third cause relates to the early stage of type 2 diabetes, where insulin resistance and delayed insulin peak times often lead to pre-meal hypoglycemia, especially before lunch and dinner. Lastly, hypoglycemia is also commonly observed in some young women with specific coloring, potentially due to gastrointestinal motility issues or other reasons leading to pre-meal hypoglycemia. It is also common in patients with hepatitis or cirrhosis, where the liver's ability to output glucose is diminished, increasing the risk of hypoglycemia when fasting.

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Written by Lin Xiang Dong
Endocrinology
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How to test for hypoglycemia?

Hypoglycemia refers to a syndrome characterized by symptoms of sympathetic nerve excitation and brain cell hypoxia due to low blood glucose concentration. We usually identify hypoglycemia first by a series of symptoms. The primary symptoms of hypoglycemia are sympathetic nerve symptoms, including dizziness, palpitations, cold sweats, hunger, and pallor. If these symptoms occur, we use a glucometer to determine if the blood sugar level is below 2.8 mmol/L. If the blood sugar is below 2.8 mmol/L, one should quickly consume sugary water and energy. If the patient's symptoms are alleviated, then it is considered hypoglycemia.

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Written by Li Hui Zhi
Endocrinology
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How to alleviate hypoglycemia

In general, for hypoglycemia, if a diabetic's blood sugar falls below 3.9 or a non-diabetic's blood sugar falls below 2.8, it is considered hypoglycemia. In terms of treatment, if the patient is conscious and experiences symptoms such as dizziness, palpitations, cold sweat, and hunger, it is recommended to measure blood sugar immediately and then eat foods that quickly increase blood sugar levels, such as chocolate or candy. If hypoglycemia in a patient is not corrected in time, it can lead to coma. If the patient is comatose, it is advised to call emergency services immediately and administer a 50% glucose intravenous injection to correct the hypoglycemia.

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Written by Lin Xiang Dong
Endocrinology
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Is hypoglycemia dangerous?

For hypoglycemia that has already occurred, as long as we can accurately and promptly identify the onset of hypoglycemia and provide appropriate treatment, the hypoglycemia can be alleviated and cured. Occasional hypoglycemia is not very dangerous after being handled, but if hypoglycemia occurs frequently and does not receive timely rescue, it can cause significant damage to the human body, especially the central nervous system, causing damage to brain cells. If hypoglycemia lasts too long, it can even endanger life, leading to coma, death, etc.

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Causes of Hypoglycemia in Pregnant Women

Hypoglycemia is a relatively common clinical phenomenon in pregnant women during pregnancy, mainly manifesting as dizziness, blurred vision, and even fainting. This occurs because the metabolism of pregnant women accelerates during pregnancy, while the secretion of the islets is not correspondingly increased. This results in the physiological function of the islets being very active, which can easily lead to low blood sugar in expectant mothers, causing symptoms such as dizziness and fatigue due to hypoglycemia. Additionally, hormonal changes during pregnancy can lead to decreased appetite, nausea, vomiting, irregular eating habits, and malnutrition in pregnant women. Despite this, energy consumption still occurs, which can also lead to hypoglycemia.

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Written by Lin Xiang Dong
Endocrinology
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Hypoglycemia emergency treatment procedure

Typically, when we consider a patient might have hypoglycemia, we follow the standard diagnostic procedures. First, we measure the patient's blood sugar level; if it is below 2.8 mmol/L, there is a high likelihood of hypoglycemia. Symptoms may include palpitations, dizziness, pale complexion, lack of concentration, lethargy, or even coma. Immediate action would involve giving the patient oral glucose solution or administrating glucose intravenously, followed by monitoring the patient’s clinical symptoms and blood sugar levels. If the patient's condition significantly improves after glucose provision, we can diagnose them with hypoglycemia. This is also a critical emergency procedure for hypoglycemia, which entails timely glucose supplementation. If the patient has recurrent hypoglycemia episodes, further detailed examinations should be conducted.