Hypoglycemia is caused by what?

Written by Li Lang Bo
Endocrinology
Updated on April 21, 2025
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Hypoglycemia is most commonly seen in patients with type 2 diabetes. During the treatment of diabetes, hypoglycemia can occur due to excessive use of medication or insulin, failure to eat on time after exercise, or decreased appetite without appropriately reducing the medication. Another common cause is insulinoma, a type of tumor that secretes excessive insulin, resulting in lowered blood glucose levels. A third cause relates to the early stage of type 2 diabetes, where insulin resistance and delayed insulin peak times often lead to pre-meal hypoglycemia, especially before lunch and dinner. Lastly, hypoglycemia is also commonly observed in some young women with specific coloring, potentially due to gastrointestinal motility issues or other reasons leading to pre-meal hypoglycemia. It is also common in patients with hepatitis or cirrhosis, where the liver's ability to output glucose is diminished, increasing the risk of hypoglycemia when fasting.

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What is hypoglycemia?

Hypoglycemia is a condition characterized by abnormally low plasma glucose levels, caused by various etiologies, and clinically presents as a syndrome mainly featuring sympathetic nervous excitement and brain cell glucose deficiency. For healthy individuals, hypoglycemia is diagnosed when blood glucose levels fall below 2.8 mmol/L. For diabetic patients, hypoglycemia is diagnosed when blood glucose levels are below 3.8 mmol/L. Hypoglycemia can be categorized into fasting hypoglycemia and postprandial hypoglycemia based on its causes. Common symptoms of hypoglycemia include palpitations, fatigue, trembling hands, accelerated heart rate, sweating, mental distraction, dizziness, drowsiness, unstable gait, irritability, and even odd behaviors. In severe cases, it can lead to coma or even death.

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How is hypoglycemia treated?

The treatment for hypoglycemia is relatively simple; in most cases, it involves immediate consumption of sugar water to replenish energy, which can significantly alleviate the symptoms of hypoglycemia. If it is an occasional, single occurrence of hypoglycemia, normal status can be restored after replenishing energy. However, if hypoglycemia occurs repeatedly, it is necessary to seek timely medical treatment at a hospital to rule out some common diseases that cause hypoglycemia.

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How to alleviate hypoglycemia

In general, for hypoglycemia, if a diabetic's blood sugar falls below 3.9 or a non-diabetic's blood sugar falls below 2.8, it is considered hypoglycemia. In terms of treatment, if the patient is conscious and experiences symptoms such as dizziness, palpitations, cold sweat, and hunger, it is recommended to measure blood sugar immediately and then eat foods that quickly increase blood sugar levels, such as chocolate or candy. If hypoglycemia in a patient is not corrected in time, it can lead to coma. If the patient is comatose, it is advised to call emergency services immediately and administer a 50% glucose intravenous injection to correct the hypoglycemia.

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How to regulate hypoglycemia?

If a patient suddenly exhibits symptoms such as dizziness, palpitations, cold sweats, pallor, and hunger, we would first consider the possibility of hypoglycemia. At this time, we use a glucose meter to determine the blood sugar level. If hypoglycemia is confirmed, oral glucose water can be administered and fasting imposed, which can relieve the symptoms. If the hypoglycemia is sporadic, it is likely due to prolonged periods without eating and lack of energy. If hypoglycemia occurs frequently, it is necessary to go to the hospital promptly for examination to rule out diseases causing hypoglycemia, such as the most common cause, an insulinoma.

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How to regulate hypoglycemia

If hypoglycemia occurs repeatedly, it is necessary to go to the hospital for an examination to rule out some diseases that may cause hypoglycemia. If no apparent diseases are found after the examination, self-regulation can be considered. The methods for self-regulation include the following: Firstly, pay attention to a reasonable diet, eat regularly, balance meat and vegetables, and develop good eating habits without excessive dieting. Secondly, persist in exercising to strengthen the body, enhance physical fitness, improve immunity, and reduce the occurrence of hypoglycemia. Lastly, develop good living habits, ensure adequate sleep, avoid staying up late, avoid excessive fatigue, and balance work and rest.