Papular urticaria is a type of contact allergic disease, often related to mosquito or flea bites. It manifests as red papules or central red wheals at the site of contact, with either a red puncture mark or blisters. For such conditions, the most common treatment is anti-allergy therapy, such as topical application of calamine lotion and oral antihistamines like loratadine. If the central blister is large, it can be disinfected with iodine, punctured, and the fluid squeezed out. It is advisable to avoid keeping small animals at home, maintain a standardized diet and lifestyle habits, avoid mosquito-infested areas, and ensure that clothing and bedding at home are thoroughly sunned and disinfected.