How is polycystic ovary syndrome treated?

Written by He Bing
Obstetrics and Gynecology
Updated on September 07, 2024
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Polycystic ovary syndrome is mainly treated symptomatically, including lifestyle modifications, medication, and surgical treatment. Medication involves regulating menstrual cycles, reducing blood androgen levels, improving insulin resistance, and inducing ovulation; the main surgical treatment currently used is laparoscopic ovarian drilling.

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Written by He Bing
Obstetrics and Gynecology
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Polycystic Ovary Syndrome Pregnancy Rate

For women who plan to conceive, their biggest concern is whether polycystic ovary syndrome (PCOS) will affect their normal fertility. Normally, reproductive-aged women develop a group of 3-11 follicles each month, which after recruitment and selection, typically only one follicle fully matures and ovulates, while the other follicles degenerate after reaching a certain stage of development. However, in patients with PCOS, the ovaries contain many small and immature follicles, often more than 12. The amount of follicle-stimulating hormone secreted by the pituitary gland is not sufficient to support the development of even one follicle, leading to anovulation and infertility. For patients with PCOS who want to conceive, the greatest risk is infertility. Patients can control their weight and regulate their menstrual cycles by adjusting their lifestyle, or by using medication to induce ovulation. Generally, more than 95% of patients can successfully induce ovulation and achieve pregnancy through medication. However, the success rate of achieving pregnancy through induced ovulation after 6 attempts is only 75% to 80%. Even for those who ovulate naturally, the success rate of conception within a year is only 82%. Therefore, it is essential to be patient, as hurried efforts will not yield immediate results in treatment.

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Written by Shen Li Wen
Obstetrics and Gynecology
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How to regulate amenorrhea in polycystic ovary syndrome?

When a woman with polycystic ovary syndrome experiences amenorrhea, the first step is to observe her body type. If she is relatively obese, it is advisable to suggest controlling diet and engaging in moderate activity to reduce her weight, that is, to lower her body mass index. After doing so, some women may regain their normal menstrual cycles. For those with a normal body type or those who still have irregular menstrual cycles after losing weight, considering oral contraceptives might be suitable. These can reduce the level of androgens in the body. For women of childbearing age who still have reproductive needs, after regulating the menstrual cycle, if normal ovulation is not resumed, ovulation induction treatments can be considered to help the woman conceive normally.

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Written by He Bing
Obstetrics and Gynecology
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Can polycystic ovary syndrome be treated with surgery?

Polycystic ovary syndrome can be treated surgically. There are two methods of surgical treatment. For patients with high levels of luteinizing hormone and testosterone, laparoscopic ovarian drilling can be performed, which has advantages such as definite therapeutic effect, minimal injury, and moderate cost. Possible issues with laparoscopic ovarian drilling include ineffective treatment, pelvic adhesion, and reduced ovarian function. Previously, ovarian wedge resection was commonly used, which could lower androgen levels, alleviate symptoms of hirsutism, and increase pregnancy rates. However, due to the high incidence of adhesions around the ovaries after surgery, this method is no longer commonly used clinically.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Can polycystic ovary syndrome be cured?

Polycystic Ovary Syndrome (PCOS) is a reproductive dysfunction accompanied by abnormal glucose metabolism, constituting an endocrine disorder syndrome primarily characterized by persistent anovulation, high androgen levels, and insulin resistance. To address the three main features of PCOS, treatment options include controlling diet and increasing physical activity to enhance insulin sensitivity and reduce levels of insulin and testosterone, thereby restoring ovulation and fertility functions. Oral contraceptives, such as Diane-35, can be taken. Oral administration of Diane-35 acts on the endometrium to inhibit excessive proliferation and regulate the menstrual cycle. To reduce androgen levels, progestogens like cyproterone can be used to counteract high androgen levels. If there is high blood sugar, it is also necessary to improve insulin resistance, which can be treated with medications like metformin. (Medications should be used under the guidance of a physician, and self-medication should be avoided.)

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Written by Wang Jing Hua
Obstetrics and Gynecology
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The difference between polycystic and polycystic ovary syndrome

Some women may discover they have polycystic ovaries during occasional gynecological exams. If their menstrual cycle is regular, with good ovulation, and does not affect pregnancy, then it is just a polycystic ovarian state, not called polycystic ovary syndrome. Polycystic ovary syndrome primarily involves irregular menstruation, poor ovulation, and difficulty in becoming pregnant. The condition of polycystic ovary syndrome varies greatly among individuals; some show clear signs of high androgens or have laboratory tests indicating high androgen levels, and many people experience a significant increase in luteinizing hormone, among other symptoms. Therefore, these are two different conditions.