Lipomas are generally located in typical spots and are mostly a benign condition that does not become malignant. Lipomas have a clear capsule, are lobulated, and have a soft texture, generally not susceptible to infection causing pain. The main reasons for pain are typically frequent movement at joint areas or long-term irritation by external factors. Therefore, upon experiencing pain, different treatment measures should be adopted based on the specific situation. If the lipoma is subjected to long-term frequent friction, reducing external irritants can help alleviate the pain. If the lipoma is located at important joint areas, surgical removal may be necessary to relieve pain symptoms. If the lipoma causes an infection, anti-inflammatory symptomatic treatment should be carried out, followed by surgical treatment once symptoms have improved.