Lipoma is a common disease in our clinical practice. Most lipoma patients have a benign tumor, which is a tumorous mass of normal fatty tissue, commonly found on the limbs and trunk, with clear boundaries, lobulated, soft in texture, possibly pseudo-cystic, painless, slow-growing, and some may be very large. For deep lipomas that may have the potential for malignancy, timely surgical removal is necessary. For small lipomas, we generally observe them periodically. If the tumor is large and affects normal life or aesthetics, surgical removal can be considered. For deep lipomas, where there is a suspicion of malignant transformation, timely surgery is advisable for treatment.