Differentiation between purulent meningitis and viral meningitis

Written by Zhang Hui
Neurology
Updated on September 21, 2024
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Purulent meningitis and viral meningitis are different diseases. Purulent meningitis is caused by bacterial infection of the meninges. Viral meningitis is caused by viral invasion of the meninges. Generally, purulent meningitis is more severe, and patients may exhibit symptoms of systemic toxin poisoning, such as high fever, nausea, vomiting, sickly appearance, and general weakness. The symptoms of viral meningitis are relatively mild, and the fever is not particularly severe. Another important differentiation is based on the analysis of cerebrospinal fluid. In viral meningitis, the lumbar puncture shows that the white blood cell count is below 1000*10^6/L, and the levels of sugar and chloride are generally normal or slightly low, with protein usually mildly elevated. In purulent meningitis, the cerebrospinal fluid shows a significant increase in white blood cell count, even reaching from 1000*10^6/L to 10000*10^6/L; the protein content is significantly increased, the sugar content is markedly decreased, and chloride levels are reduced. Additionally, bacteria can be found in the cerebrospinal fluid and blood cultures in purulent meningitis, whereas viral meningitis cerebrospinal fluid cultures do not show bacteria.

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Written by Hu Bai Yu
Pulmonology
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Does meningitis cause fever?

Generally, patients with meningitis exhibit symptoms of fever, along with headaches, nausea, vomiting, or some cognitive impairments and confusion. It is advised that everyone should be cautious and distinguish the symptoms of meningitis from those of common colds, and perhaps visit the department of neurology at a hospital for proper diagnosis and targeted treatment. Under the circumstance of meningitis, it is crucial to follow the doctor's guidance and actively cooperate with the treatment. Typically, a regimen involving anti-infection and antiviral medications is necessary for about two to three weeks, and most patients have a favorable prognosis. Additionally, it is important to maintain a relaxed mood, avoid excessive stress, and drink adequate water to promote excretion.

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Written by Liu Shi Xiang
Neurology
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What are the symptoms of meningitis?

The symptoms of meningitis mainly include headache, nausea, vomiting, fever, epileptic seizures, and mental abnormalities. Severe cases may also present with disturbances in consciousness and signs of meningeal irritation, among others. Therefore, when a patient exhibits the above symptoms, the possibility of meningitis should be considered. The patient needs to promptly visit the neurology department to undergo a cranial CT scan, cranial MRI, electroencephalogram, and lumbar puncture for cerebrospinal fluid analysis to confirm the diagnosis. Treatment should be based on the test results, selecting appropriate anti-infective medications. For example, patients with viral meningitis should be treated with antiviral medications such as acyclovir and ganciclovir; patients with bacterial meningitis should be treated with potent antibacterial drugs, including carbapenems and quinolones; patients with tuberculous meningitis should receive antitubercular drugs, such as isoniazid, rifampin, and ethambutol. In addition, patients may also need symptomatic treatments such as dehydration to reduce intracranial pressure, fever reduction, and control of psychiatric symptoms. (Medication should be used under the guidance of a doctor.)

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Written by Zhang Hui
Neurology
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sequelae of meningitis

Firstly, it may cause meningitis adhesions leading to hydrocephalus. Once hydrocephalus occurs, it may leave cognitive impairments as sequela, such as slow response, memory decline, and reduced executive functions. Secondly, tuberculous meningitis might also damage cranial nerves, resulting in symptoms such as diplopia, difficulty swallowing with choking on water, and dysarthria. If it affects the facial nerve, peripheral facial paralysis and other sequelae might occur. Thirdly, it could also lead to arteritis. The occurrence of arteritis can cause arterial occlusion, leading to the formation of cerebral infarction.

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Written by Han Shun Li
Pulmonology
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What is meningitis?

Meningitis is predominantly an inflammation that occurs in the meninges and can extend to the brain parenchyma. It is generally caused by pathogenic microorganisms, including common pathogens such as bacteria, fungi, viruses, tuberculosis bacteria, etc. The most common symptoms include fever, headache, nausea, vomiting, stiff neck, etc. More severe cases can present with convulsions, disturbances of consciousness, or even coma. The condition can be mild or severe, and if not treated promptly, it can be fatal in serious cases.

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Written by Han Shun Li
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Does meningitis cause headaches?

Meningitis is an inflammation of the meninges caused by pathogenic microorganisms, such as bacteria, tuberculosis bacteria, viruses, fungi, etc., which can all cause meningitis. Common symptoms of meningitis include fever, headache, nausea, vomiting, etc., thus patients with meningitis do experience headaches. Moreover, headache is one of the most common symptoms in patients with meningitis. Often, patients suffering from headaches will experience symptoms of nausea and vomiting, which is frequently projectile, and in many cases, the headache can be alleviated after vomiting.