Does cerebral hemorrhage have a genetic basis?

Written by Tang Li Li
Neurology
Updated on September 15, 2024
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Cerebral hemorrhage is not hereditary and is not a genetic disease; it is a type of acute cerebrovascular disease. Its occurrence is related to risk factors of cerebrovascular disease, and some risk factors may be related to genetics. Therefore, having a family history of cerebral hemorrhage is considered one of the factors that can increase the incidence rate of cerebral hemorrhage in patients. For example, if a patient's parents have hypertension, diabetes, or hyperlipidemia, these risk factors can significantly increase the likelihood that the patient will also develop these conditions as they age. Long-term hypertension, diabetes, and hyperlipidemia can lead to arterial wall hardening, sometimes resulting in hyaline degeneration. When blood pressure fluctuates, it can easily form microaneurysms that rupture and bleed, thus causing cerebral hemorrhage. Therefore, although cerebral hemorrhage itself is not hereditary, hereditary-related conditions such as hypertension and diabetes might lead to its occurrence.

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Preliminary symptoms of cerebral hemorrhage

Cerebral hemorrhage is a severe and sudden onset condition that usually starts without any prodromal symptoms, manifesting as hemiplegia, severe headaches, or even coma. However, some patients may exhibit certain early symptoms, which mainly include: First, headache, which is not particularly severe, is tolerable, but typically affects the forehead and both temporal areas. Second, patients generally have very high, hard-to-control blood pressure. If the blood pressure is extremely high and difficult to manage, the possibility of cerebral hemorrhage should be considered. Third, in the early stages of cerebral hemorrhage, patients may experience symptoms such as dizziness, blurred vision, and general weakness. Overall, the early symptoms of cerebral hemorrhage are not particularly typical. If a patient with high blood pressure becomes hard to manage, experiences slight headaches, dizziness, blurred vision, and some nausea, these may be indicative of the early symptoms of cerebral hemorrhage.

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Sequelae of cerebral hemorrhage

The most common sequelae of cerebral hemorrhage is hemiplegia, which is specifically characterized by reduced muscle strength in the limbs on one side, difficulty in movement or complete immobility, often accompanied by sensory impairments on the same side, such as reduced sensation to cold, heat, pain, etc., or complete numbness. Sometimes there may also be vision loss on the affected side, as well as aphasia, headache, vertigo, and nausea.

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How is cerebral hemorrhage treated?

For patients with cerebral hemorrhage, the first step is to urgently send the patient to the local hospital for medical attention and head CT scans. This primarily determines the current location of the hemorrhage, the severity of the bleeding, including the number of intracerebral hematomas. If there are multiple intracerebral hematomas causing significant mass effect and substantial compression on the surrounding brain tissue, leading to neurological damage, emergency surgical treatment is generally recommended. If the bleeding is minor with no significant mass effect, conservative treatment is advised. Treatment can include hemostasis, brain health promotion, nerve nutrition, acid suppression, and prevention of lung infections, among other approaches.

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What should be done about cerebral hemorrhage?

Cerebral hemorrhage is a relatively serious disease. After a cerebral hemorrhage occurs, patients usually experience noticeable headaches, nausea, and vomiting. The onset is relatively rapid, and it may present clinical symptoms such as slurred speech, deviation of the mouth, and paralysis of one side of the body. In severe cases, the patient may become comatose or even die. Once diagnosed with cerebral hemorrhage, it is necessary to immediately rush to the nearest hospital for treatment. It is important to ensure the patient rests in bed, keeps their emotions stable, avoids emotional excitement, and maintains regular bowel movements without straining. If cerebral hemorrhage causes increased intracranial pressure, dehydration medications to reduce intracranial pressure can be used. Additionally, medications to protect brain cells should be used. It is crucial to actively control the patient's blood pressure and, when the condition stabilizes, to perform regular rehabilitative exercises to promote the recovery of neurological functions. If the volume of the cerebral hemorrhage is large and threatens the patient's life, neurosurgery may be needed to save the patient's life.

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Is cerebral hemorrhage dangerous?

Cerebral hemorrhage damages the central nervous system, which is our command center. Once the command center is damaged, a person's respiration, blood pressure, pulse, heartbeat, body temperature, movement, sensation, digestion, and other vital activities will be affected. The common sites for cerebral hemorrhage are in the basal ganglia, cerebrospinal fluid, pons, and cerebellum. These regions are usually important brain functional areas. Therefore, although advanced medical technology is available for treating patients with cerebral hemorrhage, the mortality and disability rates are still relatively high. Cerebral hemorrhage is a dangerous disease.