How to reduce swelling in diabetic foot depends on the condition of the swelling. If the swelling is due to a wound on the diabetic foot causing localized redness and swelling, this condition needs anti-infective treatment. It is recommended to culture the wound secretion and choose a sensitive antibiotic; if the swelling is diffuse in the foot, it is also recommended to perform an ultrasound of the lower limb vessels, including arteries and veins. If this indicates poor venous return in the lower limbs or venous thrombosis, treatment to prevent thrombosis and improve venous return should also be added.