What are the causes of acute pancreatitis?

Written by Guo Li Ming
Gastroenterology
Updated on March 24, 2025
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There are many causes of acute pancreatitis. Common primary causes include improper diet: overeating, alcohol consumption, preference for spicy or rich foods, etc. Additionally, hyperlipidemia and cholelithiasis are also reasons, along with surgical trauma such as cholangiography, gastrectomy, etc. Other diseases can also lead to acute pancreatitis, such as hypercalcemia, diabetic coma, hyperparathyroidism, rheumatism, necrotizing vasculitis, etc.; viral infections can also cause pancreatitis, and long-term use of medications can cause acute inflammation, such as tetracycline, corticosteroids, etc. Acute pancreatitis initially presents with severe, acute abdominal pain, commonly in the left, upper middle quadrant, and occasionally radiating to the back. Subsequently, vomiting, fever, and in severe cases, shock may occur. Acute pancreatitis is a type of acute abdomen and can be life-threatening. If symptoms occur, it is crucial to seek immediate hospital treatment.

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Does acute pancreatitis have anything to do with the stomach?

Acute pancreatitis is not closely related to stomach conditions, although it is sometimes associated with overeating, but it is not caused by stomach diseases in patients. Instead, it relates to lifestyle habits. The occurrence of pancreatitis is often considered to be due to biliary, alcoholic, hyperlipidemia, and idiopathic causes. In China, the most common causes are biliary and alcohol-related. Biliary causes are mainly related to gallstones, while alcohol-related causes are mostly associated with drinking. Common stomach diseases include gastritis, ulcers, and stomach cancer. These conditions can sometimes cause an increase in amylase during acute abdominal conditions, but they do not cause acute pancreatitis.

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How long does it take to cure acute severe pancreatitis?

Acute severe pancreatitis is a disease with a long treatment period and high treatment costs. Acute severe pancreatitis is pathologically staged, generally divided into the organ failure phase, also known as the inflammatory response phase. Typically, this occurs within 7 days after the onset of severe pancreatitis, during which there is a massive release of inflammatory factors, causing multiple organ failures. This stage is perilous and often requires the support of multiple organ functions, such as ventilators and hemofiltration treatments. After this inflammatory response phase, it transitions into a chronic phase of abdominal infection, which occurs approximately one week to one or two months after the onset. At this time, there is a large amount of effusion in the abdominal cavity, and some of the effusion may develop secondary infections. The main treatment at this stage involves puncture drainage of the effusion. Once an infection is detected, puncture drainage is performed on the infected site to manage the infection. Therefore, the treatment period for severe pancreatitis primarily depends on the duration of organ function support, recovery time of organ functions, and the severity of the infection. Some organ function support may be prolonged, requiring several months, and sometimes irreversible conditions occur, such as acute renal failure transitioning into chronic renal failure. Abdominal infections are more complex. If the infection is severe and recurrent, long-term puncture drainage or surgical removal of the infection may be necessary, often requiring several months of treatment.

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Does acute pancreatitis affect the rise in blood sugar?

After the onset of acute pancreatitis, pathological changes occur in the pancreas, affecting both its endocrine and exocrine functions. The endocrine function includes the secretion of insulin, which can lead to insulin resistance, impacting glucose metabolism and causing an increase in blood sugar levels. Therefore, after admission, it is routine to monitor the blood sugar levels of patients with acute pancreatitis and manage insulin resistance. Additionally, due to the increased blood sugar levels, there is a higher risk of infection in these patients. Depending on the cause of the condition, targeted treatment is necessary along with the early use of antibiotics to control the progression of pancreatitis, reduce the rate of infections, and promote recovery of the body.

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Can acute pancreatitis patients have sexual intercourse?

Patients with acute pancreatitis cannot have sexual intercourse during the acute treatment period because it can lead to physical exhaustion and further weaken the patient's condition. Therefore, during the acute phase of acute pancreatitis, the focus should be on rest, and the diet should include foods rich in vitamins and carbohydrates, such as starchy foods, fresh vegetables, and fruits. It is important to avoid overeating, greasy foods, and alcohol consumption. If patients with acute pancreatitis recover fully, and their physical strength is completely restored, they may then consider resuming sexual activity.

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Can you drink milk with acute pancreatitis?

Acute pancreatitis, especially in the early stages of an attack, does not allow for the consumption of milk. During the onset of acute pancreatitis, especially at the beginning, it is crucial to completely refrain from eating and drinking anything, as consuming food can lead to excessive secretion of stomach acid. The stimulation from the food can cause the pancreas to secrete enzymes, potentially worsening symptoms like abdominal pain and bloating associated with acute pancreatitis. For patients with acute pancreatitis, if the condition is stable and intestinal function is restored or in the recovery phase, it is permissible to drink some milk. However, it is important to avoid consuming foods that are overly greasy, spicy or stimulating, especially alcoholic beverages, as these can exacerbate the symptoms of pancreatitis or even lead to a recurrence of the condition. The diet should primarily consist of light, low-salt, low-fat fresh vegetables and fruits.