Does iron deficiency anemia cause a yellow complexion?

Written by Zhang Xiao Le

Hematology

Updated on February 19, 2025

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No matter what type of anemia, it manifests as a decrease in hemoglobin. Red blood cells are the main cells that carry oxygen, so patients with anemia will have signs of ischemia and hypoxia to some extent, and anemia manifests as pallor in the skin and mucous membranes. Since Chinese are of the yellow race, the manifestation of anemia in Chinese patients often appears as a yellowish complexion. Therefore, patients with iron deficiency anemia can have a yellowish complexion. Of course, if there is obvious yellowing of the skin and sclera in addition to the yellowish complexion, further tests such as hemolysis indicators are needed to rule out hemolytic anemia, as patients with hemolytic anemia often have concurrent jaundice.

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Written by He Li Fang

Hematology

1min 25sec

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How is iron deficiency anemia diagnosed?

The diagnosis of iron deficiency anemia includes two aspects: one is to establish whether there is anemia caused by iron deficiency, and the other is to clarify the cause of the iron deficiency. First, we need to carefully inquire and analyze the medical history, combined with the patient's physical examination, which can provide a series of clues for diagnosing iron deficiency anemia. A definitive diagnosis also requires laboratory evidence. Clinically, we can divide iron deficiency and iron deficiency anemia into three stages: iron deficiency, iron-deficient erythropoiesis, and iron deficiency anemia. The following describes the diagnostic criteria for iron deficiency anemia specifically. Iron deficiency anemia is characterized by a significant reduction in hemoglobin in red blood cells, presenting as microcytic hypochromic anemia. Its diagnostic basis includes three aspects: first, conforming to the diagnosis of iron deficiency and iron-deficient erythropoiesis; second, having microcytic hypochromic anemia; and third, effective treatment with iron supplements. These three factors together can confirm the diagnosis of this disease.

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Written by He Li Fang

Hematology

1min 14sec

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Iron deficiency anemia lacks iron.

Iron deficiency anemia is an anemia caused by the lack of stored iron in the body, affecting the synthesis of hemoglobin. It is characterized by a lack of stainable iron in the bone marrow, liver, spleen, and other organ tissues, as well as decreased serum iron concentration, transferrin saturation, and ferritin levels, typically presenting as microcytic hypochromic anemia. Thus, iron deficiency anemia refers to a deficiency of iron. Iron is an essential trace element in the human body, involved in cellular functions and metabolic processes. The body has a strict regulatory mechanism for iron metabolism to ensure that iron levels are always maintained at a normal level, referred to as iron homeostasis. Iron homeostasis relies crucially on the balance between intestinal iron absorption and the body's iron requirements. Once this balance is disrupted, problems in iron distribution, absorption, transport, and storage may occur, leading to iron deficiency anemia.

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Written by He Li Fang

Hematology

2min 6sec

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The causes of iron deficiency anemia

The causes of iron deficiency anemia primarily refer to the disruption of the normal dynamic balance between iron absorption and excretion, leading to the consumption of stored iron as well as an increased need for iron and insufficient iron intake, especially in cases of chronic blood loss, resulting in a long-term negative iron balance. The causes of iron deficiency can be divided into two main aspects: insufficient iron intake and excessive iron loss. In the first aspect, decreased iron intake includes dietary insufficiency, meaning inadequate food intake, and reduced absorption, which includes decreased absorption due to lack of stomach acid and reduced absorption following gastric surgery. Excessive iron loss includes the following eight aspects: 1) gastrointestinal bleeding, which includes bleeding caused by tumors, gastrointestinal ulcers, gastritis, as well as bleeding due to parasites and hookworm infections. It also includes bleeding caused by hemorrhoids in men and arteriovenous malformations; 2) excessive menstrual bleeding; 3) frequent blood donations; 4) multiple pregnancies in women; 5) chronic intravascular hemolysis causing hemoglobinuria; 6) hereditary hemorrhagic telangiectasia; 7) primary pulmonary hemosiderosis; and 8) coagulation disorders or the use of anticoagulants leading to iron deficiency. These eight categories all result from excessive loss of iron, causing iron deficiency which leads to iron deficiency anemia.

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Written by He Li Fang

Hematology

1min 14sec

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What is good to eat for iron deficiency anemia?

Iron deficiency anemia is a commonly seen type of nutritional anemia in clinical settings, with many causes. It can be caused by an insufficient intake of dietary iron needed to meet the body's demands. This insufficiency can also arise when the body's requirement for iron increases, or due to certain diseases, such as atrophic gastritis, lack of stomach acid, or the excessive use of antacids, which affect iron absorption. Increased bodily consumption due to conditions like diarrhea or hookworm infection can also lead to iron deficiency. For patients with iron deficiency anemia, it is generally recommended to improve the utilization of dietary iron. The first step is to modify dietary habits and lifestyle. For instance, it is suggested that vegetarians change their dietary patterns to include more iron-rich foods, such as animal liver, beef kidney, and chicken gizzards. Iron-rich vegetarian options include soy, black fungus, sesame paste, brown sugar, and dried fruits. Therefore, it is advisable for patients with iron deficiency anemia to increase their intake of these types of foods.

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Written by Li Fang Fang

Hematology

52sec

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What indicators are used to diagnose iron deficiency anemia?

For iron deficiency anemia, a complete blood count should first be considered. The blood count presenting as microcytic hypochromic anemia often suggests the possibility of iron deficiency anemia. Microcytic hypochromic anemia is characterized by a decrease in hemoglobin, a decrease in mean corpuscular volume, a decrease in mean corpuscular hemoglobin concentration, and a decrease in mean corpuscular hemoglobin. When the complete blood count indicates the possibility of iron deficiency anemia, further investigation into iron-related indices is required, such as decreased serum iron, decreased ferritin, decreased transferrin saturation, and increased soluble transferrin receptor capacity.