Characteristics of iron deficiency anemia blood picture

Written by He Li Fang
Hematology
Updated on September 12, 2024
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The clinical manifestations of iron deficiency anemia are due to the specific characteristics of anemia caused by iron deficiency and the underlying disease causing the iron deficiency. Its hematological characteristics present as typical microcytic hypochromic anemia. What does this concept mean? It refers to the values in a complete blood count where MCV is less than 80 femtoliters, MCH is less than 27 picograms, and MCHC is less than 30%. MCV refers to the average red blood cell volume, MCH refers to the mean corpuscular hemoglobin concentration, and MCHC refers to the mean corpuscular hemoglobin concentration of red blood cells. The extent of changes in red blood cell indices correlates with the duration and severity of anemia. The blood smear typically shows pale-stained red blood cells with an enlarged central pallor and varying sizes. Platelet count often tends to be high when there is concurrent bleeding and generally tends to be low in infants and children. White blood cell count is usually normal or slightly reduced, with normal differential. These are the hematological characteristics of iron deficiency anemia.

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Written by He Li Fang
Hematology
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How is iron deficiency anemia diagnosed?

The diagnosis of iron deficiency anemia includes two aspects: one is to establish whether there is anemia caused by iron deficiency, and the other is to clarify the cause of the iron deficiency. First, we need to carefully inquire and analyze the medical history, combined with the patient's physical examination, which can provide a series of clues for diagnosing iron deficiency anemia. A definitive diagnosis also requires laboratory evidence. Clinically, we can divide iron deficiency and iron deficiency anemia into three stages: iron deficiency, iron-deficient erythropoiesis, and iron deficiency anemia. The following describes the diagnostic criteria for iron deficiency anemia specifically. Iron deficiency anemia is characterized by a significant reduction in hemoglobin in red blood cells, presenting as microcytic hypochromic anemia. Its diagnostic basis includes three aspects: first, conforming to the diagnosis of iron deficiency and iron-deficient erythropoiesis; second, having microcytic hypochromic anemia; and third, effective treatment with iron supplements. These three factors together can confirm the diagnosis of this disease.

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What department should I go to for iron deficiency anemia?

Iron is one of the essential trace elements for the human body, and it is the most likely to be deficient among trace elements. Iron deficiency can lead to iron deficiency anemia, which is also identified by the World Health Organization as one of the global nutritional deficiency diseases and a major public health nutrition issue in China. According to epidemiological surveys, iron deficiency is related to the following factors: improper feeding during infancy, picky eating and nosebleeds during childhood and adolescence. In women, it is associated with excessive menstrual flow, poor nutrition, inadequate protein intake (especially low intake of animal proteins), inappropriate consumption methods of dairy products, as well as repeated pregnancies, breastfeeding, and certain diseases such as atrophic gastritis, chronic diarrhea, significant gastric resection, and hookworm infections, all of which can cause iron deficiency. Therefore, patients with iron deficiency anemia should consult the department of hematology, as iron deficiency anemia falls under the category of red blood cell disorders within hematology. Of course, infants, children, and adolescents under the age of 14 can visit pediatrics, and a portion of patients, such as pregnant and lactating women, can visit the obstetrics department.

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Prevention and treatment of iron deficiency anemia

Some cases of iron deficiency anemia are preventable, which highlights the importance of education on nutritional knowledge and maternal and child healthcare. This includes improving infant feeding practices, advocating for breastfeeding, and timely introduction of complementary foods. Women who are pregnant or breastfeeding should appropriately supplement with iron. In areas where hookworm is prevalent, large-scale parasite prevention and control measures should be implemented, and timely treatment of various chronic gastrointestinal bleeding disorders should be carried out to reduce iron loss. Additionally, increasing iron intake can help prevent and control iron deficiency anemia. Also, high-risk groups, including infants, preterm babies, twins, pregnant women, individuals who have undergone gastrectomy, and those who frequently donate blood, should prevent and supplement with oral iron supplements for treatment.

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What is good to eat for iron deficiency anemia?

The treatment of iron deficiency anemia mainly includes two aspects. One is the treatment targeted at correcting anemia caused by iron deficiency, and the other is identifying the cause of iron deficiency in the body and correcting it. Iron deficiency anemia is caused by chronic blood loss and a relative deficiency in iron intake due to increased iron demand in the body, which leads to reduced red blood cell production. The main treatment is to supplement with iron-rich medications, and one can also consume more lean meat, pork liver, duck blood, spinach, black fungus, and other foods rich in iron. For patients with iron deficiency anemia, it is crucial to identify the cause of the iron deficiency and provide targeted treatment to fundamentally resolve the issue of iron deficiency anemia.

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What is the fastest way to treat iron deficiency anemia?

Iron deficiency anemia is a type of anemia caused by a lack of storage iron in the body, affecting the synthesis of hemoglobin. It is characterized by a lack of available iron in tissues and organs such as bone marrow, liver, and spleen, with decreased serum iron concentration, transferrin saturation, and serum ferritin levels. Typically, iron deficiency anemia presents as microcytic hypochromic anemia. Iron, as one of the essential trace elements in the human body, is contained in all functioning cells and is broadly involved in metabolic processes within the body. Therefore, the treatment principle for iron deficiency anemia involves replenishing sufficient iron until normal iron stores are restored and addressing the underlying causes that led to the iron deficiency to effectively and quickly replenish iron. Oral iron supplements are the preferred treatment option for iron deficiency anemia, such as ferrous sulfate, ferrous succinate, and iron dextran which are effective oral iron agents.