Iron deficiency anemia clinical manifestations

Written by He Li Fang
Hematology
Updated on September 28, 2024
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Iron deficiency anemia presents in a variety of ways, including symptoms of anemia and iron deficiency. The main manifestation is tissue and organ hypoxia caused by iron deficiency, and severe iron deficiency anemia can lead to mucosal tissue changes and ectoderm nutritional disorders. Among the symptoms, we can find that in the early stages, the symptoms are relatively concealed and hard to detect. Patients with a slow progression can often adapt well in the early stages and are able to engage in daily work. Common symptoms of anemia include dizziness, headache, fatigue, and tiredness, along with palpitations and shortness of breath after activity, and even symptoms such as blurred vision and tinnitus. For patients with iron deficiency, specific symptoms include angular cheilitis, atrophy of the tongue papillae, glossitis, and severe iron deficiency patients may experience koilonychia, decreased appetite, nausea, and even constipation. Some patients, particularly children during their growth periods, may exhibit delayed growth and behavioral abnormalities, specifically being irritable and easily angered, having difficulty concentrating in class, and declining academic performance. A few patients may also develop pica, which is a special manifestation of iron deficiency anemia. In terms of physical signs, patients may exhibit pallor of the skin and mucous membranes, dry hair, and keratinization of the lips. Nails may be flat, lackluster, and prone to breakage, and a small number of patients may experience mild splenomegaly. These are the clinical manifestations of iron deficiency anemia.

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Written by He Li Fang
Hematology
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Diet for Iron Deficiency Anemia

Patients with iron-deficiency anemia need to undergo pharmacological treatment with oral or injective iron supplements. In addition, patient health education should be enhanced to guide them in following a scientific and reasonable diet. For example, patients who are picky eaters or have insufficient intake should change their dietary structure and lifestyle in order to increase iron intake and bioavailability. This ensures that all key nutrients involved in the production of red blood cells are sufficient. Moreover, it is necessary to increase the intake of iron-rich foods, mainly including animal liver, blood, as well as soybeans, black fungus, egg yolks, brown sugar, lean meat, sheep kidneys, dried fruits, and sesame paste.

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Written by Zhang Xiao Le
Hematology
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Does iron deficiency anemia cause tiredness?

Patients with iron-deficiency anemia can exhibit symptoms of fatigue. Anemia is characterized by red blood cells and hemoglobin levels that are below the normal range. Red blood cells are the main cells responsible for transporting oxygen in the body. Oxygen enters the blood through gas exchange in the lungs and is then delivered throughout the body by red blood cells to supply oxygen. Therefore, patients with anemia will show varying degrees of ischemia and hypoxia. In the nervous system, this can be manifested as lethargy, insomnia, frequent dreaming, tinnitus, blurry vision, fainting, and lack of concentration. As the severity of anemia increases, these symptoms may also worsen. Patients with severe anemia may exhibit significant lethargy and drowsiness.

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Written by Zhang Xiao Le
Hematology
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What is the fastest way to treat iron deficiency anemia?

The treatment of iron deficiency anemia mainly includes two aspects: one is iron supplementation, and the other is identifying and correcting the underlying cause of the anemia. Iron supplementation for patients with iron deficiency anemia can be administered orally or via intravenous infusion, the latter of which tends to be faster. Generally, hemoglobin begins to rise about a week after treatment starts, and returns to normal levels within two to three weeks. Even after hemoglobin levels normalize, iron supplementation should continue for three to six months. It is more important to identify and treat the underlying causes of anemia. Common causes of iron deficiency anemia include chronic blood loss, such as from gastrointestinal ulcers or tumors. Therefore, patients with iron deficiency anemia typically need to undergo gastrointestinal endoscopy to identify the specific cause of the iron deficiency.

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Written by He Li Fang
Hematology
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What is good to eat for iron deficiency anemia?

Iron deficiency anemia is a commonly seen type of nutritional anemia in clinical settings, with many causes. It can be caused by an insufficient intake of dietary iron needed to meet the body's demands. This insufficiency can also arise when the body's requirement for iron increases, or due to certain diseases, such as atrophic gastritis, lack of stomach acid, or the excessive use of antacids, which affect iron absorption. Increased bodily consumption due to conditions like diarrhea or hookworm infection can also lead to iron deficiency. For patients with iron deficiency anemia, it is generally recommended to improve the utilization of dietary iron. The first step is to modify dietary habits and lifestyle. For instance, it is suggested that vegetarians change their dietary patterns to include more iron-rich foods, such as animal liver, beef kidney, and chicken gizzards. Iron-rich vegetarian options include soy, black fungus, sesame paste, brown sugar, and dried fruits. Therefore, it is advisable for patients with iron deficiency anemia to increase their intake of these types of foods.

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Written by Hu Qi Feng
Pediatrics
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What are the symptoms of iron deficiency anemia in children?

Iron deficiency anemia can manifest as: 1. Gradual pallor of the skin and mucous membranes, especially noticeable on the lips, oral mucosa, and nail beds. Older children may experience dizziness, darkening before the eyes, and tinnitus. Additionally, anemia can lead to extramedullary hematopoiesis, and enlargement of the liver, spleen, and lymph nodes can occur. The younger the age and the longer the duration of the disease, the more severe the anemia and the more prominent the enlargement of the liver and spleen. 2. In terms of gastrointestinal tract: reduced appetite, pica, vomiting, diarrhea, and stomatitis may occur. 3. Nervous system manifestations include: restlessness or lethargy, lack of concentration, reduced memory, and intelligence often lower than peers of the same age. 4. Cardiovascular system: an increased heart rate may be observed, and in severe cases, cardiac enlargement and even heart failure can occur. 5. Immune system: Iron deficiency can affect hematopoietic function, often leading to reduced cell-mediated immune function and combined infections.