During an episode of atrial fibrillation, it is possible for symptoms such as chest pain to occur. Common symptoms of atrial fibrillation include palpitations, chest tightness, and shortness of breath or difficulty breathing. However, during a flare-up of atrial fibrillation, if the heart rate significantly increases, it can lead to chest pain symptoms. This is because when atrial fibrillation occurs and the heart rate significantly increases, it results in a marked shortening of the ventricular diastolic filling period. This reduces the blood volume during the diastolic filling period, further affecting the heart's pumping during the systole, leading to myocardial ischemia and causing symptoms similar to those of angina pectoris.