How to treat patent ductus arteriosus?

Written by Tang Li
Cardiology
Updated on September 01, 2024
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The arterial duct connects the main pulmonary artery to the descending aorta, serving as the primary channel for blood circulation during the fetal period. After birth, it generally becomes obstructed within a few months due to disuse; if it remains open after one year, it is referred to as patent ductus arteriosus (PDA). The length and diameter of an unclosed arterial duct vary, affecting hemodynamics differently, and consequently, prognoses differ. An unclosed arterial duct can easily induce infectious endocarditis; thus, even if the shunt is small, it is advisable to seek early interventional or surgical treatment. The surgery has a high safety success rate and can be performed at any age. However, surgery is contraindicated for patients who have developed secondary pulmonary artery obstruction and exhibit right-to-left shunting.

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Written by Tang Li
Cardiology
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Why does patent ductus arteriosus cause a decrease in diastolic pressure?

In patients with patent ductus arteriosus, since the aortic pressure is significantly higher than the pulmonary artery pressure throughout the cardiac cycle, there is continuous blood flow from the aorta into the pulmonary artery through the open duct, causing a left-to-right shunt. This increases the blood volume in the pulmonary circulation, causing dilatation of the pulmonary artery and its branches. The blood flow returning to the left heart system also increases, thereby increasing the load on the left heart and causing the left heart to enlarge. Due to the diastolic diversion of blood from the aorta to the pulmonary artery, the peripheral arterial diastolic pressure decreases and the pulse pressure increases.

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Written by Xie Zhi Hong
Cardiology
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Can you have children if you have a patent ductus arteriosus?

The ductus arteriosus refers to a channel in the fetus that, before birth, allows blood from the maternal placenta to enter the fetus's aorta through the ductus arteriosus and then circulates the blood throughout the body. This channel closes after birth, and in the vast majority of people, it closes within a year. If it remains open until reproductive age, surgery is required because an open ductus arteriosus can lead to deteriorating heart function and, in severe cases, can cause heart failure. Therefore, women with an open ductus arteriosus can have children after treatment. An open ductus arteriosus is not a hereditary disease, and regardless of whether it is present in males or females, it is not genetic and they can have children.

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Written by Xie Zhi Hong
Cardiology
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Is patent ductus arteriosus related to staying up late during pregnancy?

The arterial duct refers to a continuous duct between the main trunk of the pulmonary artery and the aorta during the embryonic period of the fetus. Through this duct, blood from the placenta can be delivered to the infant's body for tissue oxygenation. Therefore, the arterial duct is originally a normal tissue in the embryo. After the birth of the infant, the majority of arterial ducts will close within a few months. If it has not closed after one year, it can be diagnosed as congenital patent ductus arteriosus. Therefore, there is no relationship between patent ductus arteriosus and staying up late during pregnancy.

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Written by Di Zhi Yong
Cardiology
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Can you swim with patent ductus arteriosus?

If the patient has a history of patent ductus arteriosus, it is recommended that they avoid vigorous exercise, as this can increase the heart's oxygen consumption, leading to symptoms such as palpitations, chest tightness, and difficulty breathing. If it is solely this condition, sometimes palpitations may occur, leading to changes in cardiac function. It is advised not to swim. While appropriate exercise can be beneficial, swimming requires better cardiopulmonary function. It is recommended that patients undergo early surgical treatment to improve their current condition.

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Written by Xie Zhi Hong
Cardiology
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Why does patent ductus arteriosus cause differential cyanosis?

The arterial duct refers to a blood vessel connecting the main pulmonary artery and the aorta, which is normally present during fetal development. It allows blood from the mother's placenta to seep into the pulmonary artery and then enter the aorta to supply the entire body's vasculature. After the birth of an infant, this blood vessel naturally closes, typically within 3 months, and most people will have it closed by 1 year. If it has not closed after 1 year, it is referred to as patent ductus arteriosus. Because the arterial duct can connect the aorta and the main pulmonary artery, blood from the systemic circulation in the aorta may directly return to the pulmonary artery at this time. If the pulmonary artery blood flow significantly increases, it can lead to pulmonary arterial hypertension and might also cause right ventricular hypertrophy. Increased cardiac workload can lead to right-sided heart failure and may also cause left-sided heart failure. When severe left-sided heart failure occurs, a right-to-left shunt can develop, which allows pulmonary artery blood to directly enter the aorta, causing venous blood to be delivered directly into the systemic circulation. At this point, differential cyanosis occurs, characterized by bluish discoloration of the upper limbs and mild blueness in the lower limbs.