Chronic bronchitis etiology

Written by Wang Xiang Yu
Pulmonology
Updated on September 01, 2024
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The etiology of chronic bronchitis is not very clear at present, and it is now believed to be caused by the long-term interaction of various factors. The most closely related factors are harmful gases or particles that act on the respiratory tract for a long time, causing damage to some structures of the respiratory tract, such as cigarette smoke, fumes, dust, irritating gases, sulfur dioxide, nitrogen dioxide, etc. These physicochemical factors cause damage to the airways. Additionally, some infectious agents, such as bacteria, mycoplasma, or viral infections, along with some immune-related factors, are believed to play a certain role in the development of chronic bronchitis.

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The difference between acute bronchitis and bronchitis

What is the difference between acute bronchitis and bronchitis? Generally speaking, in terms of the duration of the disease, bronchitis can be classified into acute bronchitis and chronic bronchitis. Acute bronchitis is a type of bronchitis. It is often caused by infections, physical and chemical factors, allergies, etc. Patients may experience fever, cough, and expectoration, and the duration usually lasts 2 to 3 weeks. In the case of chronic bronchitis, the course of the disease is longer, with symptoms such as repeated coughing, expectoration, and wheezing, and the symptoms persist and do not improve.

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Written by Wang Xiang Yu
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COPD and chronic bronchitis differences

COPD stands for Chronic Obstructive Pulmonary Disease, also commonly referred to as chronic obstructive lung disease. It is a chronic inflammation of the respiratory tract caused by inhalation of tobacco smoke, other types of smoke, harmful gases, or particulate irritants. This inflammation persists, eventually leading to structural changes in the airways, and symptoms such as coughing up phlegm and difficulty breathing. Chronic bronchitis is diagnosed primarily based on symptoms. Also known as chronic obstructive bronchitis, it is defined by symptoms of coughing, phlegm, or wheezing lasting more than three months per year and persisting for over two years, while excluding other diseases. There is a close connection between chronic bronchitis and COPD. If a patient with chronic bronchitis experiences worsening of their condition characterized by restricted airflow, as identified through pulmonary function tests indicating airflow limitation, they can then be diagnosed with Chronic Obstructive Pulmonary Disease. However, if a patient only exhibits symptoms of chronic bronchitis and maintains normal lung function, they cannot be diagnosed with Chronic Obstructive Pulmonary Disease under such circumstances.

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Written by Liu Xiao Li
Pulmonology
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How to treat chronic bronchitis?

Chronic bronchitis is divided into acute exacerbation phase and remission phase. The treatment during acute exacerbation mainly focuses on controlling infections, and administrating antitussive, expectorant, and asthma-relieving medications. To control infections, antibiotics are empirically selected based on the common pathogens in the area. If the pathogen can be cultured, an antibiotic sensitive to the organism can be chosen based on the test. Oral administration is generally sufficient. In severe cases, medication can be administered intravenously. Patients with asthma are given bronchodilators. During the remission phase, treatment involves quitting smoking, avoiding inhalation of harmful gases and other harmful particles, strengthening physical health, preventing colds, and for patients with repeated respiratory infections, vaccines or immunomodulators may be administered to enhance immunity.

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Written by Wang Xiang Yu
Pulmonology
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Can chronic bronchitis be treated?

Chronic bronchitis, commonly known as "chronic obstructive bronchitis," is treatable. The primary symptoms of chronic bronchitis are coughing and expectoration. If the disease occurs for more than three months each year, for two consecutive years, while excluding other organic diseases, chronic bronchitis can be diagnosed. Treatment for chronic bronchitis is divided into two parts. During acute exacerbations, which typically present with worsened coughing and expectoration, increased sputum volume, or the presence of purulent sputum and possibly accompanied by wheezing and fever, the main treatment is anti-infection. The primary medications for anti-infection are antimicrobial drugs, which include macrolides, quinolones, cephalosporins, etc. Additionally, treatment can be aimed at alleviating symptoms of coughing and expectoration and might include expectorants and cough suppressants, such as ambroxol. For wheezing, medications like aminophylline or nebulized treatments may be necessary. Most of the time, patients with chronic bronchitis are in a remission phase. The primary treatment here initially involves addressing known triggers, such as insisting smokers quit and minimizing exposure to dust or harmful gases at work. Chronic bronchitis patients are encouraged to exercise moderately, strengthen their physique, and prevent colds. For patients who experience repeated respiratory infections, vaccination or immune modulators, such as BCG, may be considered. Always follow a physician’s guidance regarding specific medication use.

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Written by Wang Xiang Yu
Pulmonology
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Does chronic bronchitis cause chest tightness?

Chronic bronchitis is commonly known as "old chronic bronchitis." Its main symptoms are coughing and expectoration. These symptoms are chronic and recurrent, and the onset is gradual. Coughing and expectoration are usually more pronounced in the morning and may consist of white, sticky phlegm or frothy sputum. Occasionally, there may be blood in the phlegm, but significant hemoptysis or chest pain generally does not occur. A small portion of chronic bronchitis patients may experience wheezing, which some of them might describe as chest tightness, meaning that chest tightness can occur in some chronic bronchitis patients. Those experiencing wheezing are referred to as having asthmatic bronchitis. Additionally, some patients may also have coexisting conditions like bronchial asthma or, in later stages, chronic obstructive pulmonary emphysema, which can also lead to symptoms of chest tightness, shortness of breath, or respiratory difficulty.