Causes of Acute Appendicitis

Written by Ren Zheng Xin
Gastroenterology
Updated on September 01, 2024
00:00
00:00

The main causes of acute appendicitis are obstruction of the appendiceal lumen and concurrent infection. The appendiceal lumen is a narrow tube that communicates with the cecum at one end. Obstruction, such as a fecalith, can lead to increased pressure inside the lumen, disturbances in blood flow, damage to the mucosa, and secondary infection. It can also be caused by direct bacterial infection within the appendiceal lumen, leading to acute inflammation. Additionally, repeated diarrhea or constipation and other gastrointestinal dysfunctions can also cause circulation disturbances in the appendix, leading to bacterial invasion and acute inflammation.

Other Voices

doctor image
home-news-image
Written by Ren Zheng Xin
Gastroenterology
42sec home-news-image

How is acute appendicitis diagnosed?

The definitive diagnosis of acute appendicitis is primarily through clinical physical examination and auxiliary tests. Based on typical symptoms of acute appendicitis, such as migratory right lower abdominal pain, vomiting, nausea, fever, and a few patients may have symptoms of constipation or diarrhea. There is obvious tenderness and rebound pain when pressing on the abdomen. Additionally, an abdominal ultrasound can indicate swelling of the appendix lumen and a significant increase in appendix size. These aspects can lead to a preliminary diagnosis, and once acute appendicitis is confirmed, surgical treatment should be carried out.

doctor image
home-news-image
Written by Ren Zheng Xin
Gastroenterology
42sec home-news-image

How to medicate for acute appendicitis

Acute appendicitis is commonly treated surgically in clinical settings. Medication for acute appendicitis should be used with caution according to indications; if the appendix is not purulent, it is appropriate to use anti-inflammatory drugs to control the infection and choose sensitive antibiotics, such as quinolones. If the appendix becomes purulent or perforates, timely surgical treatment should be administered to prevent further exacerbation of appendicitis. Before and after the surgery, it is important to monitor whether the patient's symptoms and signs have significantly worsened. (Medications should be taken under the guidance of a physician and based on actual conditions)

doctor image
home-news-image
Written by Ren Zheng Xin
Gastroenterology
46sec home-news-image

Acute Appendicitis Etiology

The cause of acute appendicitis is primarily bacterial infection of the appendiceal lumen due to various reasons. The appendix itself is a narrow tube connected to the cecum. If a fecalith falls into the lumen, it can cause obstruction of the appendiceal lumen, leading to an increase in intra-luminal pressure and circulatory disturbances in the appendiceal wall. At this time, the mucosa is susceptible to damage, and bacterial invasion of the wall can cause infections of varying degrees. Additionally, gastrointestinal dysfunction, such as diarrhea or constipation, can also cause spasms of the appendiceal vessels, leading to blood supply disturbances and resulting in acute inflammation.

doctor image
home-news-image
Written by Ren Zheng Xin
Gastroenterology
47sec home-news-image

Early symptoms of acute appendicitis

The symptoms of the early stage of acute appendicitis primarily include vague abdominal pain, initially across the abdomen, then transitioning around the belly button, and after several hours, shifting to the lower right abdomen where the pain becomes localized. The early symptoms of acute appendicitis are not typically distinctive, with the onset being quite sudden, accompanied by severe abdominal pain, vomiting, and fever. Based on these typical clinical manifestations, diagnosing acute appendicitis is not difficult. Clinically, the main treatment is the surgical removal of the appendix, with laparoscopic appendectomy being the more common practice nowadays. This method involves less bleeding during the operation and a quicker post-operative recovery.

doctor image
home-news-image
Written by Ren Zheng Xin
Gastroenterology
44sec home-news-image

Which is more serious, acute appendicitis or chronic appendicitis?

Acute appendicitis is relatively common in clinical practice with severe symptoms. Compared to chronic appendicitis, acute appendicitis can cause the appendix tube to become purulent and perforate, leading to a widespread peritonitis. Severe peritonitis can cause multi-organ failure and even shock. Chronic appendicitis, on the other hand, mainly manifests as chronic abdominal pain and seldom shows signs of appendix perforation. It primarily leads to an abscess around the appendix, encapsulating the appendix and causing repetitive chronic pain, which is difficult to heal. Both acute and chronic appendicitis should be treated surgically by removing the appendix to achieve a complete cure.