Can ovarian teratomas become cancerous?

Written by Li Lin

Obstetrics and Gynecology

Updated on April 01, 2025

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Ovarian teratomas are mostly benign tumors, and it is usually sufficient to undergo tumor excision or unilateral oophorectomy. However, ovarian teratomas can become malignant, and in such cases, corresponding chemotherapy treatment should be used after surgery based on the condition.

Even after chemotherapy, malignant teratomas may recur. If the malignant teratoma recurs, further surgeries can be performed. Each surgery can reduce the malignancy of the teratoma, so surgery combined with chemotherapy is very effective for the treatment of malignant teratomas.

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Written by Sun Shan Shan

Obstetrics and Gynecology

1min 7sec

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Are teratomas mostly benign?

Ovarian teratomas belong to the category of germ cell tumors, which are divided into mature teratomas and immature teratomas. Immature teratomas are malignant and account for 1%-3% of ovarian teratomas, thus they occur relatively less frequently. These are more commonly found in young patients, with an average age of 11-19 years. Mature teratomas, also known as dermoid cysts, are benign and can account for 10%-20% of ovarian tumors and 85%-97% of germ cell tumors, comprising over 95% of ovarian teratomas. These can occur at any age, but are most common between 20-40 years, often unilateral, and may contain components such as fats, hair, and sometimes teeth and bone tissues. Thus, the majority of mature teratomas are benign tumors.

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Written by Yan Chun

Oncology

46sec

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Formation of teratoma

Teratoma is a type of tumor disease originating from germ cells, clinically classified into benign and malignant categories. The specific cause of teratoma formation is currently unclear; it is considered to be due to abnormal mutations occurring during the development of germ cell tumors, thereby forming tumors. The formation of teratomas also involves some inducing factors, such as familial genetic history. Due to specific genetic mutations in the family, the incidence of familial teratomas increases. Additionally, some external infections are also related to the occurrence of teratomas, ultimately leading to their formation.

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Written by Yan Qiao

Obstetrics and Gynecology

54sec

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How long after laparoscopic surgery for a teratoma can one have sexual intercourse?

Teratomas are predominantly benign tumors, mainly located in the ovaries, although in some patients with unique physical constitutions, ovarian tissues may also ectopically end up in the pelvic area, forming a pelvic teratoma. Whether it is an ovarian teratoma or a pelvic teratoma, the scope of the surgery is typically medium-sized. If the surgery is an open operation, it is classified as a second-level surgery, and if it is performed using laparoscopy, it should be classified as a third-level surgery. Both second and third-level surgeries fall under the medium-sized category, and patients usually recover quite quickly after the operation. Typically, we advise patients to refrain from sexual intercourse, pelvic baths, and to avoid heavy physical labor within a month post-operation.

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Written by Tao Zhong E

Obstetrics and Gynecology

53sec

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How is a teratoma diagnosed?

Teratomas mostly occur on the ovaries. Ovarian tumors generally do not show symptoms in their early stages or when they are small. They are usually discovered during physical examinations, and identified through ultrasound, which will indicate a cystic mass or a cystic-solid mass on the ovaries. Subsequently, serum tumor markers are tested to see if there is an increase. Some patients with teratomas may show a slight increase in alpha-fetoprotein. Further diagnostic steps include a pelvic MRI, which can very clearly display the nature of the tumor and some of the components within the tumor. The most common findings in teratomas include elements like hair and bones. Ultimately, a definitive diagnosis relies on pathological examination.

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Written by Zhao Xiao Dong

Obstetrics and Gynecology

48sec

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Will the teratoma recur after the ovary is removed?

For teratomas, ovarian tumor excision surgery is generally chosen. If the teratoma is too large, and the remaining ovarian tissue is insufficient, there is no need to preserve the ovary, or if the teratoma has severe torsion causing ovarian tissue necrosis, an oophorectomy is necessary. After the oophorectomy, recurrence on the same side is generally not observed, but there is sometimes a possibility of recurrence on the opposite side, though the likelihood of recurrence is very low. Generally, if one ovary is removed due to a teratoma, the recurrence rate on the opposite side is usually less than 10%. Treatment of teratomas is generally surgical, and if not treated timely, complications such as torsion may occur.