Women with bacterial vaginitis need to be treated with metronidazole, which can be either taken orally or applied as metronidazole vaginal effervescent tablets. Some women may experience recurrent bacterial vaginitis, which leads to a longer duration of medication use, potentially causing an imbalance in the vaginal flora.

Yeast naturally exists in the vagina, but the environment is usually stable due to the predominance of lactobacillus, which inhibits the growth of yeast. However, if the treatment period for vaginitis is extended, it can disrupt the vaginal environment, reduce the amount of lactobacillus, and consequently, yeast can proliferate and lead to yeast-based vaginitis.