Premature rupture of membranes causes

Written by Liu Wei Jie
Obstetrics
Updated on September 15, 2024
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The causes of premature rupture of membranes, or premature rupture of membranes, occur before labor when the membranes break. Normally, the membranes should rupture during labor when the cervix is fully dilated. Any rupture before this is called premature rupture of membranes. The main causes of premature rupture of membranes are maternal infections or cephalopelvic disproportion. Infections can cause the membranes to become fragile and thin, and movements afterwards may lead to premature rupture. Another scenario is cephalopelvic disproportion, where the fetus is relatively large and the pelvis is small, leading to changes in amniotic fluid pressure, which can also result in premature rupture of membranes.

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Written by Zhang Lu
Obstetrics
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Is premature rupture of membranes prone to infection?

After premature rupture of membranes, various aspects of impact on both the mother and the fetus can occur, but the most important is the risk of infection. After the rupture of membranes, since the amniotic cavity is connected to the vagina through the cervix, the bacteria present in the vagina can potentially enter the amniotic cavity through the cervix and cause an infection inside the amniotic cavity. Therefore, after the rupture of membranes, the most crucial action is to prevent infection, primarily using antibiotics for treatment and closely monitoring indicators of infection. Monitoring for infection after premature rupture of membranes can be done in the following ways: first, pay attention to the characteristics of the amniotic fluid, which often has an odor in case of infection; second, monitor infection indicators, including white blood cells and C-reactive protein; third, observe if the pregnant woman exhibits any symptoms of fever.

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Written by Zhang Lu
Obstetrics
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Symptoms of premature rupture of membranes infection

Premature rupture of membranes refers to the breaking of the fetal membrane before the onset of labor, followed by the leakage of amniotic fluid. The greatest risk of premature rupture of membranes is the potential to cause an infection in the amniotic cavity. The symptoms of infection due to premature rupture of membranes include the following aspects: First, the smell and color of the amniotic fluid will change. The amniotic fluid may become purulent and have a foul smell, which suggests an infection within the amniotic cavity. Second, blood tests can reveal elevated infection markers, primarily an increase in white blood cells and C-reactive protein well above the normal range. Third, the patient may experience contractions or lower abdominal tenderness and rebound pain. When there is an infection in the amniotic cavity, symptoms of peritonitis may occur, along with manifestations of contractions, presenting as episodic pain in the lower abdomen. These are the symptoms of infection from premature rupture of membranes.

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Written by Liu Wen Li
Obstetrics
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Can premature rupture of membranes be repaired?

The amniotic sac, once ruptured, cannot be repaired. It is a membrane that envelops the fetus and the amniotic fluid, providing protection against microbial invasion from the outside and preventing infection of the fetus. Once ruptured, not only can the amniotic fluid leak, leading to a decrease in its volume, but it can also lead to infections and the possibility of umbilical cord prolapse. Typically, rupture of the amniotic sac naturally leads to contractions. Therefore, if it is not yet full-term, it is important to prevent the rupture of the amniotic sac.

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Written by Yue Hua
Obstetrics and Gynecology
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Premature rupture of membranes requires what examinations?

To diagnose premature rupture of membranes, first, a pH test of the vaginal fluid must be conducted. The normal pH value of vaginal fluid in women ranges from 4.5 to 5.5, whereas the pH of amniotic fluid ranges from 7.0 to 7.5. If the membranes have ruptured prematurely, the pH value would be greater than 6.5. Additionally, a smear test of the vaginal fluid can be done by placing vaginal secretions under a glass slide and examining them under a microscope. If fern-like crystals are observed, this indicates the presence of amniotic fluid. Furthermore, an ultrasound examination can be conducted. If the ultrasound shows a rapid decrease in the amount of amniotic fluid, this can assist in the diagnosis.

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Written by Zhao Li Li
Obstetrics
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Is the risk of infection high with premature rupture of membranes?

In general, after premature rupture of membranes, there is still a significant risk of intrauterine infection. Normally, after premature rupture of membranes, it is necessary to clearly determine whether the development size of the embryo inside the uterine cavity is mature, as well as the specific amount of premature rupture of membranes and vaginal discharge. If the rupture of membranes is severe and there is a large amount of amniotic fluid flowing out of the vagina, it generally may lead to a reduction in amniotic fluid and significantly increase the risk of infection. After confirming premature rupture of membranes, it is necessary to actively use antibiotics for symptomatic treatment to prevent infections, promote fetal lung maturity inside the uterine cavity, and reduce the risk of delayed lung function development in the fetus after childbirth.