After melanoma metastasizes to the brain, it requires early treatment, which mainly includes the following measures:

First, general supportive care, such as using mannitol or glycerol fructose to reduce intracranial pressure and alleviate symptoms like headache, nausea, and vomiting if increased intracranial pressure occurs after brain metastasis;

Second, local treatment, such as whole brain radiotherapy or precise Gamma Knife surgery, to control the intracranial lesion after brain metastasis;

Third, systemic treatment, as melanoma with brain metastases indicates stage IV disease, requiring control of the condition through systemic treatments including chemotherapy, targeted drug therapy, and immunotherapy.