Osteosarcoma is a malignant tumor of the bone, and the treatment effect of moxibustion is not very good. This disease develops quite rapidly, mostly occurring at the proximal end of the tibia, the distal end of the femur, the proximal end of the humerus, among others, typically at the metaphyseal ends. Clinically, the main symptoms include persistent pain, which becomes more pronounced at night, along with local swelling, restricted movement, increased local surface skin temperature, some may show prominent veins, and patients often appear emaciated, severely looking cachectic as the disease progresses with noticeable symptoms. Radiographic examination can reveal Codman's triangle or sunburst patterns. Early detection necessitates early treatment, including surgery such as inactivation reimplantation or prosthesis implantation to sustain operation. Additionally, amputation followed by extensive chemotherapy can effectively improve the patient’s survival time. Osteosarcoma has a high chance of early pulmonary metastasis, requiring systematic treatment at a hospital. Solely using moxibustion is not very effective and has limited usefulness, but it could still be worth a try if there are no better options available.