Osteosarcoma bone metastasis symptoms

Written by Na Hong Wei
Orthopedics
Updated on September 03, 2024
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The symptoms of osteosarcoma metastasis, osteosarcoma most commonly metastasizes to the lungs. If pulmonary metastasis occurs, there are at least two prominent characteristics. The first is that most metastatic tumors are located on the surface of the lungs and are rarely within the lung parenchyma, thus, they are not difficult to detect.

The second point is that most metastatic tumors predominantly present as multiple bilateral lung metastases. Isolated unilateral lung metastasis is very rare. Therefore, this characteristic determines that osteosarcoma lung metastasis can only be managed with local wedge-shaped or segmental lung resections as the basic comfort measure. In fact, this simple surgical approach often allows for complete removal of the metastatic tumors while preserving most of the normal lung tissue.

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Is there a cure for osteosarcoma?

Osteosarcoma is treatable, but it requires proper medical treatment. Currently, adjuvant chemotherapy significantly improves the five-year survival rate for osteosarcoma. The main treatment approach is still surgery as part of a comprehensive therapy. Specifically, the first step involves adequate preoperative chemotherapy, generally no fewer than six sessions over about eight weeks, or approximately two months. After this, patients often experience reduced pain, weight gain, improved positioning of the tumor, and a decrease in tumor size. Depending on the specific situation, a decision is made on the type of surgery to be performed—whether to amputate, preserve the limb, install a prosthetic, or use artificial bone as a replacement. Postoperative chemotherapy is usually also required to help ensure that the tumor does not recur and to increase the five-year or ten-year survival rate. Therefore, the current five-year survival rate for osteosarcoma has increased from the previous 40%-50% to about 80%. So, as long as one chooses the right hospital and the right treatment plan, and maintains confidence, osteosarcoma is usually treatable.

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Is chondrosarcoma cancer?

Chondrosarcoma is broadly cancer, but in medical terms, we wouldn’t necessarily phrase it that way; we simply describe chondrosarcoma as a type of malignant tumor, and currently, its treatment outcomes are not very good. Generally, when we talk about cancer, we’re referring to malignant tumors that originate from epithelial tissue, including cancers like stomach cancer, lung cancer, colon cancer, and liver cancer, which all derive from epithelial tissues. However, because chondrosarcoma originates from mesenchymal tissue, which includes muscle, cartilage, blood vessels, and nerves, malignant tumors that occur in these areas are usually called sarcomas. Sarcomas are definitely malignant, but to strictly call them cancer is not particularly precise.

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The difference between sarcoma and osteosarcoma

The relationship between sarcoma and osteosarcoma is very simple; it is a relationship of containment where sarcoma includes osteosarcoma. Simply put, the concept of sarcoma is broader, and osteosarcoma is a subtype under it. Sarcoma itself also includes malignant tumors occurring in blood vessels, fat, nerves, and muscles, such as angiosarcoma, liposarcoma, rhabdomyosarcoma, and leiomyosarcoma, and, of course, osteosarcoma. However, both sarcoma and osteosarcoma are malignant tumors, and it's important to clarify this concept. Moreover, osteosarcoma is more common in young people.

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What is osteosarcoma?

Firstly, osteosarcoma is a common type of malignant tumor, characterized by a mechanism that produces bone-like tissue. It has multiple subtypes and can also develop into a secondary osteosarcoma. Secondly, it commonly occurs in adolescents. Thirdly, it typically affects the proximal femur, distal tibia, and proximal humerus. Fourthly, common osteosarcomas are generally spindle-shaped, often located near joints. The surface may have elevated skin temperature and sometimes superficial vein distension is apparent. It often involves the entire bone, including the periosteum, cortical bone, and bone cavity. Generally, the tumor appears as a very fine greyish-white or brownish-red fish-flesh-like change. Osteosarcoma is a malignant tumor and is particularly prone to lung metastasis. According to tumor staging, it is at least stage IIB, indicating that it should be detected, diagnosed, and treated early. The earlier the treatment, the better the outcome and the higher the five-year survival rate.

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Can hot compresses relieve pain for osteosarcoma?

Osteosarcoma has very limited pain relief effects through simple or pure hot compresses. As the lesion progresses, hot compresses can become completely ineffective or have very unclear effects. Clinical manifestations include pain and swelling, with local formation of lumps or tumor-like appearances. It can also affect the joint mobility around it, and even cause atrophy of limbs and muscles. In terms of treatment, it still relies on early surgical excision, but the prognosis is still not very optimistic.