Does osteosarcoma require amputation?

Written by Wang Cheng Lin

Orthopedics

Updated on August 31, 2024

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Do osteosarcomas require amputation? In the past, the likelihood of amputation for treating osteosarcoma was very high. However, currently, the rate of amputation is very low, and the limb-salvage rate is very high. This is due to a new chemotherapy protocol in medical practice, which involves initial chemotherapy followed by surgery, and then continued chemotherapy post-operatively. The limb-salvage rate with this treatment plan can reach about 75% to 80%. Therefore, currently, most osteosarcoma patients do not require amputation. Unlike the past, where amputation rates were very high, today's medical approach is very advanced, generally resulting in a very high rate of limb preservation for osteosarcoma patients.

Other Voices

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Written by Na Hong Wei

Orthopedics

59sec

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Osteosarcoma is a type of cancer.

Osteosarcoma is a relatively common type of malignant bone tumor in clinical practice. It mainly occurs near the ends of the humerus, including the area around the head of the humerus, and at the distal end of the femur, near the femoral condyles, as well as the proximal tibia, close to the tibial plateau. These are its common sites. It predominantly affects teenagers, generally those under 18 years of age. The main symptoms include: firstly, persistent and worsening pain that gradually intensifies and does not alleviate, with the notable characteristic being that the pain is more severe at night than during the day; secondly, the appearance of spindle-shaped tumors around the joints, particularly at the three aforementioned common sites, often accompanied by redness, warmth, pain in the superficial skin, and even prominent superficial veins; thirdly, osteosarcoma is a type of malignant tumor, classified as grade 2B among malignant tumors. Its main feature, apart from local symptoms, is its propensity for metastasis, with the lungs being the most likely site of metastasis.

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Written by Wang Cheng Lin

Orthopedics

42sec

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Early symptoms of osteosarcoma

The early symptoms of osteosarcoma are generally not very obvious, manifesting only as occasional pain and discomfort around the joints, which can limit joint mobility. As the condition progresses, this intermittent pain becomes continuous. Additionally, the intensity of the pain gradually increases, and lumps may also appear, which typically cause pain when pressed. As the disease further advances, patients may also experience low-grade fever, anemia, and liver and kidney failure, eventually leading to pathological fractures. Therefore, for the treatment of osteosarcoma, early detection and early treatment are crucial for the best prognosis.

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Written by Wang Cheng Lin

Orthopedics

48sec

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How to prevent osteosarcoma

From the perspective of osteosarcoma itself, prevention should involve active exercise, a healthy lifestyle, and a regular schedule. All of these can play a preventive role. However, as of now, there is no clear cause of what triggers osteosarcoma, and it is still unknown. For patients with osteosarcoma, we need to achieve early diagnosis and early treatment. Since many osteosarcomas occur in adolescents, if your child complains of bone pain and feels lumps, and more severely, experiences joint functional impairment, parents must be vigilant. It is advised for the patient to go to a hospital and have an imaging test done to confirm if it is caused by osteosarcoma. Therefore, early diagnosis and early treatment are best.

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Written by Guan Yu Hua

Orthopedic Surgery

1min 44sec

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Osteosarcoma Causes

Osteosarcoma is the most common malignant tumor of the bone and typically presents without symptoms in its early stages. The cause of osteosarcoma is unknown, and it often goes undetected until it has reached a moderate or advanced stage. It commonly develops at the distal end of the femur near the knee joint, at the proximal end of the tibia, or at the proximal end of the humerus, primarily at the end of the growth plate. The pain associated with osteosarcoma is usually persistent, especially severe at night, and can lead to symptoms such as anemia or general wasting. The tumor's surface may be warm to the touch, with prominent veins visible, and radiographic imaging might show a Codman's triangle, indicative of sunlight-like radiation patterns, as well as bone destruction and clear periosteal reaction. Surgical treatment is typically pursued, with amputation being the most common procedure, though limb-sparing surgeries are possible if the tumor is detected early enough. Some cases metastasize, most commonly to the lungs, requiring continued high-dose chemotherapy post-surgery to prolong survival. Generally, the five-year survival rate for osteosarcoma can exceed 50% with early diagnosis and treatment. The chances of survival heavily depend on the individual’s constitution, the timing of tumor detection, and the surgical intervention. The exact causes of osteosarcoma are unclear, and the potential for metastasis complicates treatment. Therefore, early surgical intervention is crucial for improving survival rates and enabling patients to maintain a normal life and work activities.

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Written by Guan Yu Hua

Orthopedic Surgery

1min 14sec

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During the treatment of osteosarcoma

Osteosarcoma is a highly malignant tumor of the bone, primarily presenting with pain, elevated skin ridges, and bulging veins. Radiological examination often reveals bone abnormalities, such as Codman's triangle and periosteal reactions due to sun exposure. If there is no metastasis in the early stages, limb amputation surgery can be performed, as well as limb-sparing surgeries involving devitalization and reimplantation or prosthetic implantation. Post-operative treatment involves high-dose chemotherapy, which can inhibit the growth of the bone tumor and extend the patient's survival time. There is a high probability of lung metastasis occurring in the early stages of the disease. If metastasis occurs, the survival time may be significantly reduced. Early diagnosis of this disease is crucial, and it must be treated with chemotherapy as early as possible. With the rapid development of chemotherapy, the five-year survival rate for osteosarcoma can increase to over 50%. Thus, early detection, early treatment, early surgery, followed by chemotherapy and radiotherapy are essential to prolong the patient's survival time.