Does myasthenia gravis require hospitalization?

Written by Zhang Hui
Neurology
Updated on December 23, 2024
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Myasthenia Gravis is a type of neuroimmune disease within the field of neurology which fundamentally stems from issues with the patient's own immune function. Whether hospitalization is necessary depends critically on the severity of the disease. If Myasthenia Gravis manifests only as ocular symptoms, such as ptosis and double vision, hospitalization is generally not necessary. It is important to take certain medications, primarily cholinesterase inhibitors and corticosteroids, but regular outpatient follow-ups are essential. However, if Myasthenia Gravis is generalized, with noticeable whole-body weakness, particularly if accompanied by swallowing difficulties and coughing while drinking, hospitalization is required. If a myasthenic crisis occurs, presenting with respiratory muscle weakness and breathing difficulties, hospitalization is certainly needed, and admission to the ICU might be necessary.

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Written by Zhang Hui
Neurology
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Myasthenia gravis should not use what medicine?

Myasthenia gravis is a neuromuscular junction disease in neurology, primarily due to some synaptic dysfunction, leading to pathological fatigue and general weakness in patients. Patients with myasthenia gravis often experience exacerbation of the disease due to fatigue or infection, and certain medications can severely affect synaptic function, worsening the condition, and are therefore not to be used. The medications to avoid mainly include the following types: The first type is aminoglycoside antibiotics, which can exacerbate the transmission at the neuromuscular junction. Second, quinolone antibiotics should also be avoided as much as possible. Third, some antiarrhythmic drugs can also decrease the excitability of the fascia and are not recommended. Additionally, some drugs like morphine, benzodiazepines, and receptor blockers should also be contraindicated or used with caution.

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Written by Liu Hong Mei
Neurology
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Can metronidazole be used for myasthenia gravis?

Patients with myasthenia gravis must use ornidazole with caution and under the guidance of a doctor because the side effects of ornidazole may exacerbate myasthenia gravis. However, ornidazole is not relatively or absolutely contraindicated for patients with myasthenia gravis. Generally, the patient's side effects are observed, and if myasthenia gravis is aggravated, the use of ornidazole is recommended to be cautious or prohibited. Ornidazole can cause neurological reactions, including headache, fatigue, dizziness, trembling, limb numbness and weakness, convulsions, mental confusion, epileptic seizures, ataxia, and consciousness disturbances, and may cause peripheral nerve damage.

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Written by Liu Hong Mei
Neurology
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Is myasthenia gravis an autoimmune disease?

Myasthenia gravis is an autoimmune disease that primarily affects the neuromuscular junction, leading to abnormalities in acetylcholine receptors. This can cause weakness in some or all skeletal muscles, which easily fatigues, particularly after activity or exertion, with symptoms worsening. Symptoms can be alleviated after rest or treatment with cholinesterase inhibitors. As an autoimmune disease, myasthenia gravis often co-occurs with other autoimmune disorders such as hyperthyroidism, thyroiditis, systemic lupus erythematosus, and rheumatoid arthritis. Symptoms of myasthenia gravis typically lessen in the morning and worsen after activity, showing a pattern of being lighter in the morning and heavier in the evening.

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Written by Zhang Hui
Neurology
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How to alleviate myasthenia gravis?

Myasthenia gravis is a disease of the department of neurology and its incidence is not low, it is also relatively common clinically. The treatment of myasthenia gravis mainly includes the following points: First, if patients with myasthenia gravis also have a thymoma, it is recommended to surgically remove the thymoma as soon as possible, which can significantly alleviate the symptoms of myasthenia gravis and reduce the amount of medication needed. Second, provide patients with some medication, mainly some drugs that suppress the immune response, including some corticosteroids. The use of corticosteroids is relatively complex, and must be gradually increased or decreased under the advice of a doctor. Do not stop taking them on your own. There are also some drugs that are cholinesterase inhibitors, which can increase the content of acetylcholine in the synaptic gap, alleviating the patient's symptoms. In addition, research has confirmed that some new immunosuppressive agents can also be used in the treatment of myasthenia gravis. In summary, the treatment of myasthenia gravis is a comprehensive subject and must be tailored according to the patient's condition.

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Written by Zhang Hui
Neurology
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Myasthenic crisis includes

Myasthenia Gravis, a type of immune inflammatory disease of the nervous system, is mainly caused by the production of abnormal antibodies in the body. Myasthenic crisis can endanger the life safety of patients, affecting respiratory function. There are mainly three types of crises: The first type of crisis is the myasthenic crisis, which is also the most common. Generally, it is caused by the progression of the disease itself, often due to insufficient anticholinesterase drug dosage. The second type of crisis is the cholinergic crisis, caused by an overdose of anticholinesterase drugs, resulting in symptoms like muscle tremors in patients. The third type is the paradoxical crisis, which occurs due to insensitivity to anticholinesterase drugs, leading to severe respiratory difficulties. It is essential to handle a myasthenic crisis promptly, maintain the patient's airway clearance, and use a ventilator for treatment if necessary.