Can third-stage syphilis be completely cured?

Written by Zhu Zhu

Dermatology

Updated on September 17, 2024

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Third-stage syphilis and late-stage syphilis generally have a longer duration, with many cases exceeding two years. Third-stage syphilis can cause damage to the cardiovascular and nervous systems, and there may be residual symptoms after improvement. However, with persistent long-term standard treatment, it is still possible to achieve a cure. Therefore, if one contracts third-stage syphilis, it is crucial to adhere to the treatment and cooperate actively with the therapy.

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Written by Zhu Zhu

Dermatology

53sec

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Can third stage syphilis be detected?

Third-stage syphilis can be detected. Syphilis is divided into primary, secondary, and tertiary stages, with the severity progressively increasing from the primary to tertiary stage, making tertiary syphilis a relatively advanced and serious condition. It can be detected by measuring the titers in serum, although the titers in tertiary syphilis may be lower than in the primary and secondary stages, and may sometimes present as negative. However, through the symptoms of tertiary syphilis, particularly some complications affecting the skin, cardiovascular system, bones, joints, and other organs, combined with the titer levels, it can definitely be detected.

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Written by Zhu Zhu

Dermatology

36sec

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How long is the latency period for tertiary syphilis?

The latency period of tertiary syphilis is not clearly defined, but it is certain that once tertiary syphilis appears, the duration of illness in patients generally exceeds two to three years, meaning the latency period is at least two to three years long. Of course, some patients may reach five to ten years. This depends on each individual's resistance as well as the virulence and amount of the virus. Additionally, if one contracts tertiary syphilis, it is crucial to seek timely and proper treatment, as it may be life-threatening.

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Written by Luo Hong

Dermatology Department

52sec

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Can syphilis antibodies be detected during the hard chancre stage?

During the hard chancre phase of syphilis, a portion of cases can test positive for Treponema pallidum, although some tests may return negative results. In such cases, it is advisable to retest after one month. The earliest detectable antibodies for Treponema pallidum are usually of two types: a Treponema pallidum-specific antibody, which appears earlier than the non-specific antibodies. There are tests for non-specific antibodies, commonly referred to as RPR or TRUST, which are standard practices in major hospitals. Therefore, in early-stage syphilis or primary syphilis with hard chancre, it is possible to find Treponema pallidum-specific antibodies positive, RPR or TRUST negative, or both negative. If syphilis is strongly suspected in such cases, a retest is recommended after one month.

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Written by Zhu Zhu

Dermatology

1min 18sec

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Early symptoms of syphilis

Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum, with the disease course within two years referred to as early syphilis. Not all infected individuals display symptoms; asymptomatic syphilis is also known as latent syphilis. Symptomatic early syphilis primarily manifests as either primary or secondary syphilis. The main symptom of primary syphilis is a chancre, typically occurring as a clear-bordered ulcer in the genital area. It is flesh-colored and neither painful nor itchy. Several weeks after the chancre heals, secondary syphilis can develop, characterized by a rash that may resemble other skin conditions. Common manifestations include macules, papular macules, copper-red papules on hands and feet, flat condyloma, and syphilitic alopecia. Individuals who suspect they may have been exposed to syphilis should visit a hospital for a blood test to detect syphilis antibodies. Antibodies can usually be detected four weeks after infection, and a negative result three months later can rule out syphilis.

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Written by Xiong Hong Hai

Infectious Disease

37sec

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Which is more serious, syphilis or AIDS?

Syphilis and AIDS, between the two, AIDS is more serious. This is because AIDS currently cannot be cured, and requires long-term regular intake of antiretroviral drugs. Syphilis, on the other hand, can be completely cured. In the early stages of syphilis, such as primary and secondary syphilis, the treatment is often very effective and also very convenient. Generally, a treatment course of two to three weeks can cure most syphilis infections. Therefore, between syphilis and AIDS, AIDS is more serious. These two diseases often occur simultaneously because both are transmitted sexually.