What are the circumstances in which a tetanus shot should not be administered?

Written by Zhang Peng
General Surgery
Updated on December 25, 2024
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Tetanus is a strict anaerobic bacterium. Clinically, for deeper contaminated wounds, especially those contaminated by soil or punctured by rusty iron objects, an active injection of tetanus vaccine is recommended. Generally, for superficial scratches or clean and shallow wounds, as long as proper wound cleaning is performed, it is usually not necessary to administer a tetanus shot. For patients who have completed a full course of immunization or booster immunization within the last ten years and have high antibody levels in the body, if the wound is small, superficial, and free of foreign bodies or necrotic tissue residue, it is not necessary to inject the tetanus vaccine. For wounds that are larger, deeper, and heavily contaminated, with substantial residues of foreign bodies and necrotic tissue, or in cases where thorough wound cleaning is not achievable, an enhanced injection of tetanus antitoxin or immunoglobulin should be administered.

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Written by Xu Jun Hui
General Surgery
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How to administer a tetanus shot if it is negative?

A negative tetanus needle test indicates that the patient is not allergic to the tetanus antitoxin and can continue with intramuscular injections, typically administered in the upper arm or buttock muscles, in doses ranging from 1000 to 3000 units each time. If the infection is severe or the tetanus injection is not timely, the dosage may be appropriately increased, generally by one to two times. The purpose of administering tetanus antitoxin treatment is to prevent infection by Clostridium tetani, an anaerobic bacterium. For patients with deep wounds or heavily contaminated wounds, such as those contaminated with soil or rust, Clostridium tetani can easily colonize. Therefore, for such patients, it is essential to perform tetanus antitoxin treatment while cleaning and dressing the wound.

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Written by Zhang Peng
General Surgery
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What should I do if I drink alcohol with tetanus?

If there are high risk factors for tetanus infection after an injury, and alcohol has been consumed, it is generally advisable to wait until sobriety before conducting relevant skin tests. Currently, there is no clear research on the relationship between alcohol consumption and an allergy to tetanus antitoxin. It is not very clear whether alcohol impacts the results of a skin test, so it is safer to perform the test after sobering up. Since the consequences of a tetanus infection can be severe, and the tetanus injection itself carries a certain risk of anaphylactic shock, which can lead to multiple organ problems and even be life-threatening, it is generally safer to conduct the skin test after sobering up and then proceed with the timely injection treatment. If the skin test is positive, tetanus immunoglobulin should be chosen promptly.

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Written by Zhang Peng
General Surgery
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How long does a tetanus shot last?

Tetanus prophylactic treatment is advised to be carried out as soon as possible, ideally within 24 hours for optimal effectiveness. However, prevention treatment can still be carried out after 24 hours, as long as the disease has not manifested. Current research does not prove that tetanus prevention is ineffective after this period. Therefore, timely and effective preventive treatment should be implemented following high-risk tetanus infection factors, choosing either tetanus antitoxin or tetanus immunoglobulin. The incubation period for tetanus infection is about a week, and as long as the disease has not manifested, choosing appropriate medication can have a preventive effect. Tetanus antitoxin and tetanus immunoglobulin have different metabolic cycles; the half-life of tetanus antitoxin is generally about three days, whereas tetanus immunoglobulin can last up to three weeks.

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Written by Li Jin Quan
General Surgery
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Can tetanus be treated?

Tetanus is a specific infectious disease, most cases of which present as muscle tension and rigidity. Specific symptoms include difficulty opening the mouth, a sardonic smile, stiff neck, and opisthotonus. In severe cases, difficulties in breathing or even cessation of breathing can occur, and in critical cases, the heartbeat may also stop. Once tetanus occurs, it is crucial to seek active treatment at a hospital. With proper and systematic treatment provided by hospitals, most patients can be cured. Therefore, tetanus is a curable infectious disease.

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Written by Li Jin Quan
General Surgery
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How long does it take for tetanus to develop?

Tetanus is a specific type of infection caused by the toxin produced by the growth and reproduction of Clostridium tetani, which enters the body through damaged skin and mucous membranes and thrives in an anaerobic environment. Clinically, it is mainly characterized by lockjaw, muscle rigidity, and muscle spasms. After being infected with tetanus, people generally show symptoms within seven to eight days; in quick cases, symptoms can appear within twenty-four hours, while in longer scenarios, the onset can take several months or even years.