Is the tetanus shot safe?

Written by Xu Jun Hui
General Surgery
Updated on March 17, 2025
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It is safe to receive tetanus treatment at an accredited hospital. There are two types of tetanus injections: the tetanus toxoid, which requires a skin test, and the tetanus immunoglobulin, which does not require a skin test. Alcohol consumption must be avoided before using the tetanus toxoid. If the skin test is negative, the injection is safe. The other type, tetanus immunoglobulin, can be used directly without a skin test. Tetanus injections from reputable manufacturers and hospitals are safe. However, some people may experience symptoms such as pain, nausea, and vomiting during the tetanus injection. Typically, these symptoms can be alleviated and disappear with symptomatic treatment after the injection.

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Written by Gao Sen
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Does a tetanus shot hurt?

Tetanus shots are certainly painful, but why do they hurt? Firstly, because a skin test is needed for tetanus, which primarily involves injecting the drug under the skin of the forearm to form a small bump about 0.5cm in diameter. It is known that there are abundant nerve endings under the skin, so the injection of the drug can cause local swelling and compress the surrounding nerves, and the drug can also cause an irritation response in the surrounding nerves, which is why tetanus shots are painful.

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Written by Ma Xian Shi
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Tetanus incubation period

Tetanus is a specific infection caused by Clostridium tetani. The incubation period of tetanus is generally seven to eight days, but it can be as short as 24 hours or as long as several months to years. Patients with shorter incubation periods have a worse prognosis. Tetanus occurs within two weeks after injury in 90% of patients, presenting symptoms such as general weakness, headache, dizziness, chewing difficulty, local muscle tightness, painful pulling, and increased reflexes. Typical symptoms include muscle tonic contraction, opisthotonus, and facial expressions characterized by lockjaw and a sardonic smile.

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Written by Zhang Peng
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What should I do if I drink alcohol with tetanus?

If there are high risk factors for tetanus infection after an injury, and alcohol has been consumed, it is generally advisable to wait until sobriety before conducting relevant skin tests. Currently, there is no clear research on the relationship between alcohol consumption and an allergy to tetanus antitoxin. It is not very clear whether alcohol impacts the results of a skin test, so it is safer to perform the test after sobering up. Since the consequences of a tetanus infection can be severe, and the tetanus injection itself carries a certain risk of anaphylactic shock, which can lead to multiple organ problems and even be life-threatening, it is generally safer to conduct the skin test after sobering up and then proceed with the timely injection treatment. If the skin test is positive, tetanus immunoglobulin should be chosen promptly.

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Written by Li Jin Quan
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Can tetanus be cured?

In clinical practice, the vast majority of tetanus patients can be cured, provided there are no severe complications. Typically, tetanus is caused by the toxin produced by Clostridium tetani within the human body, leading to a specific type of infection. Clinically, it usually manifests as muscle tension and rigidity, and some patients might experience lockjaw, difficulty opening the mouth, a sardonic smile, and even stiff neck and opisthotonos. Severe cases can lead to difficulty breathing, respiratory arrest, or even cardiac arrest. Tetanus patients should go to the hospital for systematic, formal treatment and care. The vast majority of tetanus patients can be cured.

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Written by Xu Jun Hui
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How many times do you need to get a tetanus shot?

If tetanus vaccination is required due to an injury, one injection is sufficient. There are two types of tetanus shots. One is called tetanus antitoxin, which is extracted from horse serum. For this, a skin test is needed to check for allergies. If allergic, tetanus antitoxin cannot be used; if not, it can be used. The other type is refined tetanus antitoxin, also known as tetanus immune globulin, extracted from human serum. This type does not require a skin test and can be used directly, but it is more expensive than tetanus antitoxin. If tetanus treatment is needed for each injury, one injection is sufficient.